Polymerization of ethylene oxide under controlled monomer addition via a mass flow controller for tailor made polyethylene oxides

Abstract

The synthesis of polymers with controlled molecular and structural parameters is challenging due to the required purity of the chemicals and the exclusion of protic impurities and oxygen in particular in the case of an anionic process as shown here.

Synthesis and Characterization of Cationic Hydrogels from Thiolated Copolymers for Independent Manipulation of Mechanical and Chemical Properties of Cell Substrates

“…[24] In addition, gaseous ethylene oxide polymerization requires special equipment to minimize the risk of poisoning, even for laboratoryscale polymerizations, making it difficult to develop novel PEGbased polymers beyond those that are commercially available. [25] In the last decade, thiolated polymers have attracted considerable interest due to their potential applications in controlled drug delivery as well as the formation of hydrogels for regenerative medical applications. [26][27][28] Recently, much progress was achieved in various thiol-related chemistries, in particular radical thiol-ene [29] and thiol-yne [30] chemistries as well as thiol-Michael addition to activated double bonds.…”

Core-Crosslinked Fluorescent Worm-Like Micelles for Glucose-Mediated Drug Delivery

“…These properties are beneficial for active targeting via functionalized micellar surfaces . PEO can be synthesized using different initiators via anionic ring-opening polymerization (AROP) . Further blocks can either be attached in a one pot synthesis by addition of a second monomer after complete consumption of ethylene oxide (EO) because of the living character of this polymerization technique, or in a second polymerization step .…”

“…33 PEO can be synthesized using different initiators via anionic ring-opening polymerization (AROP). 34 Further blocks can either be attached in a one pot synthesis by addition of a second monomer after complete consumption of ethylene oxide (EO) because of the living character of this polymerization technique, or in a second polymerization step. 35 The initiator can also carry a functional group to enable the attachment of small molecules for active cell targeting to the surface of the nanoparticle, often realized via click chemistry.…”

Facile Cu(I) Loading for Adsorptive C3H6/C3H8 Separation Through Double Cu(II) Salts Incorporation Within Pores With Unsaturated Fe(II) Sites

“…Separation of light olefins from light paraffins is crucial because ethylene and propylene are important precursor materials 1 . Ethylene is used as a raw material for producing various chemical compounds such as polyethylene and ethyl benzene 2 . Propylene is a precursor for obtaining many valuable materials including isopropyl alcohol and propylene oxide 3 .…”

“…1 Ethylene is used as a raw material for producing various chemical compounds such as polyethylene and ethyl benzene. 2 Propylene is a precursor for obtaining many valuable materials including isopropyl alcohol and propylene oxide. 3 However, separation of olefin/paraffin mixtures is challenging because olefin and paraffin have similar properties.…”