Polymeric films containing pomegranate peel extract based on PVA/starch/PAA blends for use as wound dressing: In vitro analysis and physicochemical evaluation

Costa, Nubya Nascimento; Lopes, Lohanna de Faria; Ferreira, Daiana Freitas; Prado, Elisabeth Maria López de; Severi, Juliana Aparecida; Resende, Juliana Alves; Careta, Francisco de Paula; Ferreira, Maria Carolina Pimentel; Carreira, Lílian Gasparelli; Souza, Sarah Oliveira Lamas de; Cotrim, Monique Alvarenga Pinto; Boeing, Thaise; Andrade, Sérgio Faloni de; Oréfice, Rodrigo Lambert; Villanova, Janaína Cecília Oliveira

doi:10.1016/j.msec.2020.110643

Cited by 54 publications

(24 citation statements)

References 59 publications

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“…In the case of PD, different thermal events were observed with peak temperatures ranging between 100 and 235 °C, which were associated to the loss of surface water and volatile low molar mass components of the dye (approximately 12 wt% of the initial mass) [49]. Other losses were also observed at temperatures around 235 °C and 440 °C, which were probably related to the loss of organic material and thermal decomposition of the different components present in PD [50] which were degraded to phenolic acids and aldehydes by deglycosylation and ring opening reactions [51]. This behaviour indicates a poor high temperature resistance for the studied natural pigment.…”

Section: Thermal Stability Of Pdnpsmentioning

confidence: 99%

Anthocyanin Hybrid Nanopigments from Pomegranate Waste: Colour, Thermomechanical Stability and Environmental Impact of Polyester-Based Bionanocomposites

et al. 2021

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In the present work, anthocyanin (ACN) hybrid nanopigments were synthetized by using a natural pomegranate dye (PD) and calcined hydrotalcite (HT) and montmorillonite (MMT) nanoclays. A wide colour gamut was obtained with MMT-based nanopigments ranging from reddish to bluish hues caused by structural transformations of ACNs at different pH values. However, a buffer effect was observed with HT obtaining samples a similar final colour regardless of the synthesis conditions. Nanopigments added with a biomordant extracted from pomegranate peels showed a different colour compared to the incorporation of a commercial mordant due to the intrinsic colouring properties of the pomegranate bioadditive. The developed nanopigments were incorporated at 7 wt% loading to produce novel polyester-based bionanocomposites which were characterized in terms of thermal, mechanical and colour properties. The encapsulation of PD into the nanoclays improved its thermal stability, in particular for MMT-based nanopigments. The pH changes observed during the nanofillers synthesis affected the final colour of the MMT-based nanocomposites, inducing a general increase in ∆E* and a decrease in gloss values. Slight improvements were obtained in terms of elastic modulus for MMT-based polymer samples confirming the applicability of the developed bionanocomposites as colouring and reinforcement materials. A very similar environmental profile was obtained for MMT and HT-based nanofillers showing MMT-based nanopigments a slightly better general behaviour. The results of the LCA study evidenced the suitability of the processes used in this work to the circular bioeconomy approach through sustainable food waste management and the production of bioplastics using waste substrates.

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Section: Thermal Stability Of Pdnpsmentioning

confidence: 99%

Anthocyanin Hybrid Nanopigments from Pomegranate Waste: Colour, Thermomechanical Stability and Environmental Impact of Polyester-Based Bionanocomposites

et al. 2021

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“…Therefore, it cannot be surprising that different materials of unique properties and forms are applied in modern dressings. Especially polymers, of both synthetic and natural origin, garner great attention in the field; among the naturally occurring polymers employed in dressing production, chitosan [107], hyaluronic acid [108], keratin [109], gelatin, starch [110], silk fibroin [111], heparin [112,113], collagen [114], sericin [115], sodium alginate [116,117], zein [118], and konjac glucomannan [119][120][121] can be enumerated [122,123]. On the other hand, polyvinyl alcohol (PVA) [110], polylactic acid (PLA) [124], polyacrylic acid (PAA) [110], polyethylene glycol (PEG) [125], polycaprolactone (PCL) [126], and polyvinylpyrrolidone (PVP) [127] are examples of synthetic polymers applied for that purpose [128].…”

Section: Modern Wound Dressing Materials and Nanomaterialsmentioning

confidence: 99%

Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing

et al. 2022

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Wound management is the burning problem of modern medicine, significantly burdening developed countries’ healthcare systems. In recent years, it has become clear that the achievements of nanotechnology have introduced a new quality in wound healing. The application of nanomaterials in wound dressing significantly improves their properties and promotes the healing of injuries. Therefore, this review paper presents the subjectively selected nanomaterials used in wound dressings, including the metallic nanoparticles (NPs), and refers to the aspects of their application as antimicrobial factors. The literature review was supplemented with the results of our team’s research on the elements of multifunctional new-generation dressings containing nanoparticles. The wound healing multiple molecular pathways, mediating cell types, and affecting agents are discussed herein. Moreover, the categorization of wound dressings is presented. Additionally, some materials and membrane constructs applied in wound dressings are described. Finally, bacterial participation in wound healing and the mechanism of the antibacterial function of nanoparticles are considered. Membranes involving NPs as the bacteriostatic factors for improving wound healing of skin and bones, including our experimental findings, are discussed in the paper. In addition, some studies of our team concerning the selected bacterial strains’ interaction with material involving different metallic NPs, such as AuNPs, AgNPs, Fe3O4NPs, and CuNPs, are presented. Furthermore, nanoparticles’ influence on selected eukaryotic cells is mentioned. The ideal, universal wound dressing still has not been obtained; thus, a new generation of products have been developed, represented by the nanocomposite materials with antibacterial, anti-inflammatory properties that can influence the wound-healing process.

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“…The swelling index, Q, was investigated in phosphate-buffered solution (PBS) over 60 min, at room temperature, according to the procedure adopted from Costa et al [35]. PVA/TPS packaging samples, with dimensions of 50 mm × 15 mm × 0.01 mm, were dried in an oven at 105 • C until a constant mass was reached, after which the samples were placed in vials containing 50 mL of PBS solution.…”

Section: Study Of Filmsmentioning

confidence: 99%

Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer

et al. 2021

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Meeting the challenge of circularity for plastics requires amenability to repurposing post-use, as equivalent or upcycled products. In a compelling advancement, complete circularity for a biodegradable polyvinyl alcohol/thermoplastic starch (PVA/TPS) food packaging film was demonstrated by bioconversion to high-market-value biopigments and polyhydroxybutyrate (PHB) polyesters. The PVA/TPS film mechanical properties (tensile strength (σu), 22.2 ± 4.3 MPa; strain at break (εu), 325 ± 73%; and Young’s modulus (E), 53–250 MPa) compared closely with low-density polyethylene (LDPE) grades used for food packaging. Strong solubility of the PVA/TPS film in water was a pertinent feature, facilitating suitability as a carbon source for bioprocessing and microbial degradation. Biodegradability of the film with greater than 50% weight loss occurred within 30 days of incubation at 37 °C in a model compost. Up to 22% of the PVA/TPS film substrate conversion to biomass was achieved using three bacterial strains, Ralstonia eutropha H16 (Cupriavidus necator ATCC 17699), Streptomyces sp. JS520, and Bacillus subtilis ATCC6633. For the first time, production of the valuable biopigment (undecylprodigiosin) by Streptomyces sp. JS520 of 5.3 mg/mL and the production of PHB biopolymer at 7.8% of cell dry weight by Ralstonia eutropha H16 from this substrate were reported. This low-energy, low-carbon post-use PVA/TPS film upcycling model approach to plastic circularity demonstrates marked progress in the quest for sustainable and circular plastic solutions.

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Polymeric films containing pomegranate peel extract based on PVA/starch/PAA blends for use as wound dressing: In vitro analysis and physicochemical evaluation

Cited by 54 publications

References 59 publications

Anthocyanin Hybrid Nanopigments from Pomegranate Waste: Colour, Thermomechanical Stability and Environmental Impact of Polyester-Based Bionanocomposites

Anthocyanin Hybrid Nanopigments from Pomegranate Waste: Colour, Thermomechanical Stability and Environmental Impact of Polyester-Based Bionanocomposites

Composite Membrane Dressings System with Metallic Nanoparticles as an Antibacterial Factor in Wound Healing

Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer

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