Polymeric Drug Carrier Systems in the Brain

Domb, Abraham J.; Ringel, Israel

doi:10.1016/b978-0-12-185291-7.50016-3

Cited by 10 publications

(1 citation statement)

References 30 publications

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“…This is particularly useful for drugs that are toxic or have severe side effects. For example, polymeric nanoparticles can be used to deliver anticancer drugs directly to tumour cells [13].…”

Section: Applications Of Polymeric Drug Delivery Systemmentioning

confidence: 99%

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review

Tripathi,

Bhardwaj,

Tiwari

et al. 2024

Preprint

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The last 20 years have seen significant advancements in polymeric drug delivery methods. A formulation or a system that makes it possible for a medicinal ingredient to be injected into the body is known as polymeric drug delivery1. The key choice for many novel medication delivery methods is made achievable by biodegradable and bio-reducible polymers. The research's prospects for practical applications have necessitated the field's development—the choice for a lot of new drug delivery systems. The prospects of the research for practical applications are required for the development in the field. Polymeric drug delivery methods have been developed from natural polymers like arginine, chitosan2, dextrin, polysaccharides, poly (glycolic acid), poly (lactic acid), and hyaluronic acid. Regarding polymeric drug delivery1, synthetic polymers such as poly(2-hydroxyethyl methacrylate), poly(N-isopropyl acrylamide), poly(ethylenimine), dendritic polymers, biodegradable, and bioabsorbable polymers have all been considered. Polymeric drug delivery has also been addressed by focusing on drug-free macromolecular therapies, biomimetic and bio-related polymeric systems, and targeting polymeric drug delivery. Pharmaceutical fields are seeing a tremendous rise in the development of polymeric drug delivery methods based on natural and manmade polymers. The successful advancements in the utilization of biocompatible and bio-related copolymers and dendrimers in cancer treatment, including their application as vehicle systems for highly effective anticancer medications3. A new paradigm for the development of polymeric drug and gene delivery systems will be possible through the fusion of viewpoints from the synthetic and biological domains.

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Section: Applications Of Polymeric Drug Delivery Systemmentioning

confidence: 99%

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review

Tripathi,

Bhardwaj,

Tiwari

et al. 2024

Preprint

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Polyanhydrides

et al. 2002

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Introduction Historical Outline Synthesis Polyanhydride Structures Unsaturated Polymers Aliphatic‐aromatic Homopolymers Soluble Aromatic Copolymers Poly(ester‐anhydrides) Fatty Acid‐based Polyanhydrides Amino Acid‐based Polymers Modified Polyanhydrides and Blends Characterization Composition by 1 H‐NMR Molecular Weight Crystallinity Infra‐red and Raman Analysis Surface and Bulk Analysis Stability Fabrication of Delivery Systems In vitro Degradation and Drug Release Biocompatibility and Elimination Applications Outlook and Perspectives Patents

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Synthesis of Poly (Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain

Domb

Kubek

2001

Blood—Brain Barrier

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Polymeric Drug Carrier Systems in the Brain

Cited by 10 publications

References 30 publications

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review

Polyanhydrides

Synthesis of Poly (Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain

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Polymeric Drug Carrier Systems in the Brain

Cited by 10 publications

References 30 publications

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability &amp; Solubility of BCS Class II, IV Drugs: A Review

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability &amp; Solubility of BCS Class II, IV Drugs: A Review

Polyanhydrides

Synthesis of Poly (Carboxyphenoxypropane-Sebacic Anhydride) for the Delivery of Drugs to the Brain

Contact Info

Product

Resources

About

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review

The Role of Biodegradable Polymers in Nano Carrier-based Drug Delivery System to Enhance Oral Bioavailability & Solubility of BCS Class II, IV Drugs: A Review