Polymeric Acid Doped Polyaniline Nanotubes for Oligonucleotide Sensors

Abstract

Template-free, self-assembled polyaniline (PANI) nanotubes were prepared in a solution of poly(methyl vinyl etheralt-maleic acid) (PMVEA) by oxidative polymerization using ammonium persulfate as the oxidant. The weight ratio of the polymeric acid to aniline in the solution had a significant effect on the size of the polyaniline nanotubes as determined by SEM. The outer diameter of the nanotubes increased from 65 nm to 160 nm with increased levels of PMVEA in the reaction solution from 1 to 4 wt/v%. The PANI/PMVEA nanotubes were characterized by FTIR and cyclic voltammetry. The nanotubes were used to construct a simple electrochemical oligonucleotide (ODN) sensor where ODN probes were covalently grafted onto the residual carboxylic acid functionalities on the nanotubes. The potential pulse amperometry technique was used to obtain a direct and fast electrochemical readout.

Piezoresistive effect in spin-coated polyaniline thin films

“…One of the exceptions is conducting polyaniline [3][4][5], for which researchers are looking with considerable interest for applications in organic electronic devices, such as organic light-emitting diodes (OLEDs) [6,7], Schottky barrier diodes [8,9], organic electrodes [7], electro-chromic displays [10], sensors [11,12] and energy storage devices, including supercapacitors and batteries [13][14][15]. Although polyaniline has large potential as a future material in next-generation electronic devices, the low electrical conductivity and stability of polyaniline, as well as its solubility have limited its applications [16] Despite the interest of polyaniline for applications in the area of sensors [17,18] there are not enough data and investigations on the piezoresistive properties of this polymer.…”

Electrical Conductivity Studies of Polyaniline Nanotubes Doped with Different Sulfonic Acids

“…Many techniques have been used to synthesize PANI nanostructure such as stirring [6][7][8], static placement, [9] sonication [10][11][12], and emulsion polymerization [13][14][15][16]. Particularly, conducting polymer nanotubes and nanofibers have received growing interest in recent years due to their unique properties and promising potential applications in nanodevices [17][18][19][20][21]. The investigation of nanostructured conducting polymers has great importance for both scientific and technological points of view.…”

Conducting polymers for electrochemical DNA sensing

“…The hybridization events were detected by differential pulse voltammetry (DPV) measurement using methylene blue as an indicator and a detection limit of 1.0 pM was reported. Zhang et al demonstrated a templatefree method to prepare polyaniline nanotubes from a solution containing poly(methyl vinyl ether alt-maleic acid) (PMVEA) and using ammonium persulfate as the oxidant [118]. The obtained nanotubes were deposited onto a glassy carbon electrode, followed by grafting of amino-modified ODN probes onto the residual carboxylic acid functionalities on the nanotubes.…”