Polyhydroxyethylmethacrylate-based magnetic DNA-affinity beads for anti-DNA antibody removal from systemic lupus erythematosus patient plasma

Lysozyme purification with dye-affinity beads under magnetic field

“…Magnetic separation is requiring a simple apparatus, composed to centrifugal separation. Recently, there has been increased interest in the use of magnetic carriers in biomolecule coupling, nucleic acid and protein purification [18][19][20][21][22].…”

Immunoglobulin G depletion from human serum with metal-chelated beads under magnetic field

“…(ii) These bio-ligands are difficult to immobilise in the proper orientation; (iii) antibody may leak from the matrix and such contamination cannot, of course, be tolerated in clinical applications. In addition, the depletion of IgG in human serum is employed successfully for the treatment of immune disorders including systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis, alloimmunization and cancer [10][11][12][13][14].…”

Efficient removal of albumin from human serum by monosize dye-affinity beads

“…The removal of IgG is commonly achieved by immobilizing protein A of protein G onto the affinity resins, which binds to the Fc region of the IgG [10], but specific antibodies can also be used. In addition, the depletion of IgG in human plasma is employed for the treatment of immune disorders including systemic lupus erythematosus, rheumatoid arthritis, myasthenia gravis, alloimmunization and cancer [11][12][13][14].…”