Polyethylene Glycol–Promoted Dialkyl, Aryl/Heteroaryl Phosphonates

Naidu, K. Reddi Mohan; Dadapeer, E.; Reddy, C. Bhupendra; Rao, A. Papa; Reddy, C. Suresh; Raju, C. Naga

doi:10.1080/00397911.2010.518279

Cited by 14 publications

(6 citation statements)

References 8 publications

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“…The –NH protons gave a singlet in the region of (10.78–8.01) and the methyleneoxy protons resonated as multiplets at (4.06–4.01) [35]. The alkenes protons gave a singlet in the region of 6.73–6.31.…”

Section: Resultsmentioning

confidence: 99%

Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Naidu

Khalivulla

Rasheed

et al. 2013

IJMS

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Section: Resultsmentioning

confidence: 99%

Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Naidu

Khalivulla

Rasheed

et al. 2013

IJMS

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“…We studied the PEG-400-mediated synthesis of 3-hydroxy-3-(pyridin-2-ylmethyl)indolin-2-ones (Raghu, Rajasekhar, Reddy, Reddy, & Reddy, 2013), alkyl phosphonates (Mohan Naidu et al, 2011), α-aminophosphonates (Rao, Jayaprakash, Nayak, & Reddy, 2011), α-aminonitriles (Kumar, Babu, Srinivasulu, Kiran, & Reddy, 2007), and its modified catalytic action in the form of PEG-SO 3 H for the synthesis of α-aminophosphonates (Reddy et al, 2012) has driven us to explore its application for the study of some other organic compounds. In this hierarchy, we studied the PEG-400-mediated synthesis of 1,2-disubstituted benzimidazoles and accomplished them with good yields.…”

Section: Public Interest Statementmentioning

confidence: 99%

Polyethylene glycol (PEG-400): An efficient medium for the synthesis of 1,2-disubstituted benzimidazoles

et al. 2015

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“…This protocol has also been applied for the phosphonylation of some alkyl and aryl halides, however, the study is limited to specific functional groups. 406 5.3.2. Quinolines.…”

Section: Tetrahydroisoquinolines and Tetrahydroquinolinesmentioning

confidence: 99%

Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity: An Update 2004–2024

Mayorquín-Torres,

Simoens,

Bonneure

et al. 2024

Chem. Rev.

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The increasing importance of azaheterocyclic phosphonates in the agrochemical, synthetic, and medicinal field has provoked an intense search in the development of synthetic routes for obtaining novel members of this family of compounds. This updated review covers methodologies established since 2004, focusing on the synthesis of azaheterocyclic phosphonates, of which the phosphonate moiety is directly substituted onto to the azaheterocyclic structure. Emphasizing recent advances, this review classifies newly developed synthetic approaches according to the ring size and providing information on biological activities whenever available. Furthermore, this review summarizes information on various methods for the formation of C–P bonds, examining sustainable approaches such as the Michaelis–Arbuzov reaction, the Michaelis–Becker reaction, the Pudovik reaction, the Hirao coupling, and the Kabachnik–Fields reaction. After analyzing the biological activities and applications of azaheterocyclic phosphonates investigated in recent years, a predominant focus on the evaluation of these compounds as anticancer agents is evident. Furthermore, emerging applications underline the versatility and potential of these compounds, highlighting the need for continued research on synthetic methods to expand this interesting family.

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Polyethylene Glycol–Promoted Dialkyl, Aryl/Heteroaryl Phosphonates

Cited by 14 publications

References 8 publications

Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Synthesis of Bisindolylmethanes and Their Cytotoxicity Properties

Polyethylene glycol (PEG-400): An efficient medium for the synthesis of 1,2-disubstituted benzimidazoles

Synthetic Methods for Azaheterocyclic Phosphonates and Their Biological Activity: An Update 2004–2024

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