Polyether sulfone/hydroxyapatite mixed matrix membranes for protein purification

Sun, Jiatong; Wu, Lishun

doi:10.1016/j.apsusc.2014.04.123

Cited by 27 publications

(9 citation statements)

References 33 publications

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“…Heparin [ 26 ] and vitamin E [ 27 ] have been successfully blended into hydrophobic polymers, such as PSf and PES. Other added materials can be used as adsorbents, like activated carbon (charcoal) [ 21 ], zeolite [ 28 ], and hydroxyapatite (HAP) [ 29 ]. Zeolites, on the other hand, are microporous, aluminosilicate minerals commonly used as commercial adsorbents and catalysts.…”

Section: Dialysis Membranementioning

confidence: 99%

“…Recently, inorganic nanoparticles like carbon nanoparticles (carbon nanotube and graphene) and metal oxide nanoparticles (titanium dioxide and iron oxide) were used as nanofillers in HD membranes [ 28 , 29 ]. Nanoparticles are particles with a size between 1 and 100 nm.…”

Section: Dialysis Membranementioning

confidence: 99%

“…Other previously used adsorbents in the membrane include hydroxy appetite (HAP). Although its application in HD is yet to be seen, HAP has good adsorption to protein and is usually used in the medical field due to its biocompatibility and bioactivity [ 29 ]. HAP can be incorporated into an HD membrane to improve the membrane’s adsorption capacity towards middle-sized proteins.…”

Section: Adsorptive Membrane/sorbentmentioning

confidence: 99%

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Dialysis Membranes for Acute Kidney Injury

et al. 2022

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Mortality and morbidity rates among critically ill septic patients having acute kidney injury (AKI) are very high, considering the total number of deaths after their admission. Inappropriate selection of the type of continuous renal replacement therapy and inadequate therapy become the immediate causes of these issues. Dialysis is a commonly used treatment intended to prolong the life of AKI patients. Dialysis membranes, which are the core of dialysis treatment, must be properly selected to ensure fair treatment to the patients. The accumulation of certain types of molecules must be dealt with using the right membrane. Whether it is low-flux, high-flux, or adsorptive type, the dialysis membrane should be chosen depending on the condition of the patients. The selection of dialysis membranes should also be based on their effect on the treatment outcomes and well-being. All these options are needed to serve the patients of different clinical settings. The use of dialysis membranes is not restricted to conventional haemodialysis, but rather they can be employed in haemoperfusion, haemofiltration, haemodiafiltration, or a combination of any two of them. This review focuses in-depth on different types of dialysis membranes, their characteristics, and approaches in addressing the issues encountered in patients having AKI with sepsis and/or multiorgan failure in intensive care units.

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Section: Dialysis Membranementioning

confidence: 99%

Section: Dialysis Membranementioning

confidence: 99%

Section: Adsorptive Membrane/sorbentmentioning

confidence: 99%

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Dialysis Membranes for Acute Kidney Injury

et al. 2022

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“…To further improve these thermodynamic parameters, it would be meaningful to adopt a cross-linking agent that avoids conjugating with the human IgG binding site of Protein A. As the latest examples of protein purification adopted similar membranes, Sun and Wu [30] have proposed the bovine serum albumin (BSA) separation using mixed matrix membranes (MMMs) comprising of hydroxyapatite (HAP) inside a PES matrix. The BSA adsorption capacity of HAP particles in MMMs reached a maximum (29.4 mg/g membrane) at a pH of 7.…”

Section: Determination Of the Human Igg Adsorption Capacity Of Affinimentioning

confidence: 99%

Preparation and characterization of Protein A-immobilized PVDF and PES membranes

Akashi¹,

Kuroda²

2015

Express Polym. Lett.

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“…Because of biocompatible and bioactive properties of HA [24], it has been used for purification of biomolecules [25][26][27][28][29][30], controlling drug delivery applications and engineering bone tissue matrix [31,32]. In addition (HA/ polymer) has got enhanced properties according to pure HA as an adsorbent, such as prevents the aggregation and coagulation of HA, and provide better adsorptive features.…”

Section: Introductionmentioning

confidence: 99%