2020
DOI: 10.3201/eid2610.191711
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Polyester Vascular Graft Material and Risk for Intracavitary Thoracic Vascular Graft Infection1

Abstract: Prosthetic vascular graft infections of the thoracic aorta are rare but can be fatal. Our comparison of collagen- and gelatin-coated grafts showed that collagen-coated grafts were associated with increased biofilm formation and bacterial adherence in vitro and with higher rates of perioperative vascular graft infections in vivo.

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Cited by 17 publications
(16 citation statements)
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“…In addition, the risk factor for the new graft material is difficult to prove due to the diversity of vascular graft infections. Vascularization potential, reduced thrombogenicity, and secure pseudointima growth are key parameters that could affect the successful integration and functionality of prosthetic vascular grafts [ 200 ].…”
Section: Vascular Applicationsmentioning
confidence: 99%
“…In addition, the risk factor for the new graft material is difficult to prove due to the diversity of vascular graft infections. Vascularization potential, reduced thrombogenicity, and secure pseudointima growth are key parameters that could affect the successful integration and functionality of prosthetic vascular grafts [ 200 ].…”
Section: Vascular Applicationsmentioning
confidence: 99%
“…The highest care should be taken perioperatively, as most infections are due to the surgical treatment [25]. Therefore, perioperative infection must be prevented, as the consequences for the patient are often severe [26]. A planned glove change could prevent possible unintentional contamination.…”
Section: Tears and Double Glovingmentioning
confidence: 99%
“…However, severe trauma or insufficient blood supply caused by large-scale defects can cause serious consequences, such as claudication, sores, organ dysfunction, necrosis, or even death [ 4 , 5 , 6 ]. At present, vascular grafts are widely used clinically to prevent severe vascular injury, such as polyurethane [ 7 ], polyester [ 8 ], expanded polytetrafluoroethylene (ePTFE) [ 9 ], etc. However, the repair of vascular structures is not a single graft but a complex repair process.…”
Section: Introductionmentioning
confidence: 99%