Polycystic ovary syndrome: A review for dermatologists

Housman, Elizabeth; Reynolds, Rachel V.

doi:10.1016/j.jaad.2014.05.007

Cited by 66 publications

(57 citation statements)

References 62 publications

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“…4 Other associations include obstructive sleep apnea, nonalcoholic steatohepatitis, and psychiatric illnesses, such as depression, anxiety, and eating disorders. 5 Patients with PCOS are commonly first seen by a dermatologist. 6 Diagnosis is mainly clinical.…”

Section: Introductionmentioning

confidence: 99%

Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

Jain

Singh

et al. 2018

Int J Adv Med

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Background: Dermatologists often play a significant role in its management. Cutaneous features of hyperandrogenism in Polycystic ovarian syndrome (PCOS) have varied presentation. Aim of this study was the pattern of dermatologic manifestations in polycystic ovarian disease in northern Indian females.Methods: Patients registering for treatment of polycystic ovarian disease at Dermatology outpatients department during April 2016 to March 2017 formed the study population. Residents interviewed the study subjects at the OPD. General physical examination, systemic examination, breast and pelvic examination, along with detailed dermatological examination were conducting after taking the history. Hormonal analysis was performed after an overnight fasting using enzyme immunoassay.Results: FSH and LH levels were 5.05±1.86 IU/L and 8.14±5.21 IU/L respectively. Testosterone levels were found to be 61.01±25.32 ng/dl. DHEAS levels among them were 130.05±41.21μg/dl. Two commonest cutaneous manifestations were hirsutism and acne seen in 83.8% and 59.5% of subjects. Female pattern hair loss was seen in 45.6% females. Three most frequent hormonal abnormalities noted in our study subjects were raised L/H ratio, testosterone and LH levels seen in approximately 45%, 35% and 21% cases.Conclusions: The cutaneous manifestations of PCOS reserve a major role in its management by dermatologists. A lifestyle modification along with systemic treatment remains mainstay of treatment. Monitoring for the foreseen cardiovascular risks should start early to downgrade the morbidity.

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Section: Introductionmentioning

confidence: 99%

Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

Jain

Singh

et al. 2018

Int J Adv Med

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“…Патогенез данного заболевания еще недостаточно изучен, но в настоящее время СПКЯ считается сложным полиэтиологичным расстройством, включающим в себя аномалии гипоталамо-гипофизарной системы, стероиодогенез и инсулинорезистентность [4].…”

Section: North-western State Medical University Named After Iimechnunclassified

Dermatological Aspects of Significance of Hyperandrogenizm for Polycystic Ovary Syndrome

Zaslavskiy¹,

Prokopenko²,

Danielyan³

2018

СПНО (MPSE)

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В статье проведен анализ значения симптомов гиперандрогении при синдроме поликистозных яичников (СПКЯ) как актуальная проблема в практике дерматолога. Рассматривается необходимость изучения данного синдрома как диагноза трех наук: дерматологии, эндокринологии и гинекологии. Цель исследования состоит в дифференцировании действительно диагностически значимых от ложных симптомов для выявления изучаемого заболевания. В ходе исследования было выявлено, что себорея, андрогенная алопеция не доказали большой значимости в диагностике синдрома поликистозных яичников. Акне в большинстве случаев является физиологическим проявлением, транзиторным состоянием или просто не несет значения в диагностике. Обработка данных исследований показала, что при разных когортах степень распространенности указанных заболеваний не зависела от наличия синдрома у пациенток. Тогда как гирсутизм и черный акантоз можно считать основополагающими симптомами данного заболевания. Актуальность исследования связана прежде всего с тем, что синдром поликистозных яичников -это важный в диагностике симптомокомплекс, так как он напрямую влияет на репродуктивную функцию женщин, а значит и в целом на процент рождаемости, и важно понимать, что успех в эффективной борьбе с синдромом поликистозных яичников состоит в совместной работе дерматолога, эндокринолога и гинеколога. Ключевые слова: синдром поликистозных яичников, гиперандрогения, гирсутизм, черный акантоз, акне, андрогенная алопеция, себорея. The article analyzes the significance of the symptoms of hyperandrogenia in the syndrome of polycystic ovaries (PCOS) as the actual problem in the practice of dermatologist. The necessity of studying this syndrome as a diagnosis of three sciences -dermatology, endocrinology and gynecology -is considered. The purpose of the study is to differentiate the real diagnostic symptoms from the false one in order to identify the disease being studied. The study revealed that seborrhea, androgenetic alopecia did not prove much significance for the diagnosis of polycystic ovary syndrome. In most cases acne is a physiological issue, a transient state or simply does not carry any significance for diagnosis. The analyses of the studies showes that for different cohorts the prevalence of these diseases did not depend on the presence of the syndrome in patients. While hirsutizim and acanthosis nigricans can be considered as key symptoms of this disease. The relevance of the study is primarily concerned with the fact that the polycystic ovary syndrome is the important factor for the diagnosis of a symptom, since it directly affects the reproductive function of women, and thus the birth rate. It is important to understand that the success of an effective fight against PCOS Ovary is a joint work of a dermatologist, endocrinologist and gynecologist. DERMATOLOGICAL ASPECTS OF SIGNIFICANCE OF HYPERANDROGENIZM FOR

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“…Elevated concentration of this hormone is characteristic of PCOS, indicating that ovarian hyperactivity can be decreased by the reduction in insulin secretion. In many clinical trials, lifestyle modification, through insulin and free androgen level reduction, caused the regaining of normal ovulation [25,26].…”

Section: Insulinorresistencementioning

confidence: 99%

“…The obesity, hirsutism, acne and alopecia seems do have an important role in the development of this conditions [25].…”

Section: Psychological Complicationsmentioning

confidence: 99%

Diabetes Mellitus and Polycystic Ovary Syndrome: Beyond A Dermatological Problem

Marques¹,

Silva²,

Colmonero³

et al. 2017

Diabetes Case Rep

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Background and aim: Polycystic ovarian syndrome is a common endocrine disorder in reproductive age, with unknown etiology and a variable clinical presentation. Recognizing polycystic ovary syndrome in women presenting with oligo-ovulation and hyperandrogenism offers an important opportunity to begin a life-long conversation about prevention and treatment of a condition that has a multi-system impact on affected women. Recognition offers the chance for providers and patients to engage in discussions about prevention and early treatment of metabolic derangements. This review aims to review the polycystic ovarian syndrome and the approach to the metabolic complications such as insulin resistance and associated hyperinsulinemia.

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Polycystic ovary syndrome: A review for dermatologists

Cited by 66 publications

References 62 publications

Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

Dermatological Aspects of Significance of Hyperandrogenizm for Polycystic Ovary Syndrome

Diabetes Mellitus and Polycystic Ovary Syndrome: Beyond A Dermatological Problem

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