“…In general, these findings are accordant with previous studies with binary mixtures of PAHs in vitro, reporting scarce antagonist effects in favour of agonist and potentially synergic responses and effects, depending on concentration of the compounds and endpoint (e.g. Staal et al, 2007;Tarantini et al, 2011). Nonetheless, antagonist effects resulting from PAH interactions have already been reported, especially for CYP-related responses, as it may be suspected from the present findings (see Jarvis et al, 2014, for a review).…”