Polybrominated diphenyl ethers in food and associated human daily intake assessment considering bioaccessibility measured by simulated gastrointestinal digestion

‘Towards a unified approach for the determination of the bioaccessibility of organic pollutants’

“…Experiments with different fish species such as oriental weather fish and bighead carp concluded that high lipid content of fish resulted in lower bioaccessibility results as lipids are not water soluble (Xing et al, 2008). This finding is contradicted by Yu et al (2011) who reported that bioaccessibility of PBDEs in fish increased with increasing fat content of the matrix, the bioaccessibility range was 5.2-105.3 for ΣPBDEs. They considered fat globules in the stomach matrix as bioaccessible arguing that sufficient bile salts would be produced to degrade these in the human GIT.…”

Simulating long-term occupational exposure to decabrominated diphenyl ether using C57BL/6 mice: Biodistribution and pathology

“…For the BDE-209 analysis, the samples were processed as detailed in our previous reports, with some modifications (Yu et al, 2009(Yu et al, , 2011. Briefly, 100 lL of urine was diluted with 20 mL of n-hexane.…”

Polybrominated diphenyl ethers and polychlorinated biphenyls in freshwater fish from Taihu Lake, China: Their levels and the factors that influence biomagnification

“…Concentrations of PBDE and PCB, as well as lipid content, were determined with a method described in our previous study [23]. Briefly, the lyophilized samples (8 g) spiked with the surrogate standard 13 C-PCB141 (4 ng) (Cambridge Isotope Laboratories) were extracted in a Soxhlet extractor for 72 h. Lipid content of the samples was determined gravimetrically using 25% of the extracts (Supplemental Data, Table S1).…”