Abstract:Here in we present our research on electrospun polyacrylonitrile nanofiber films embedded with titania/AgNP nanoparticles for sustained antibacterial applications. Although silver possesses excellent antimicrobial characteristics and have been extensively exploited in applications where protection from microbial species and bacterial colonization is needed. Recently, it was discovered that silver may be allergic to skin and may induce detrimental side-effects such as argyria and argyrosis. Excess utilization o… Show more
“…Then, the area of bacteria growth is detected, and the diameter of the inhibition zone around the electrospun nanofiber is measured. This procedure modifications are also used ( Santos et al, 2016 ; Wahab and Al Mamun, 2020 Fig.3 a). Fig.…”
Section: Antibacterial Performance Evaluation Of Electrospun Nanofibementioning
confidence: 99%
“… Fig. 3 a. Agar disc diffusion assay showing the clear zone of inhibition around electrospun polyacrylonitrile nanofiber mats containing titania/AgNP composite nanoparticles ( Wahab and Al Mamun, 2020 ); b. FESEM images of damaged E. coli on the single-walled carbon nanotubes-polyacrylonitrile/polyurethane/polyaniline electrospun nanofiber ( Xie et al, 2020 ); c. Photographs of colonies formed by B. subtilis and E. coli in water samples before and after electrospun coated nanofbrous polyacrylonitrile with polydopamine and silver nanoparticles (cPAN-Ag1.5) nanofbrous membranes ( Wang et al, 2017 ); d. Confocal Laser Scanning Microscopy (CLSM) images of cPAN-Ag1.5 nanofbrous membranes after filtration the bacteria suspension (green dots and red dots stands for live cells and dead cells, respectively) ( Wang et al, 2017 ). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)…”
Section: Antibacterial Performance Evaluation Of Electrospun Nanofibementioning
Pathogenic contamination has been considered as a significant worldwide water quality concern. Due to providing promising opportunities for the production of nanocomposite membranes with tailored porosity, adjustable pore size, and scaled-up ability of biomolecules incorporation, electrospinning has become the center of attention. This review intends to provide a detailed summary of the recent advances in the fabrication of antibacterial and antiviral electrospun nanofibers and discuss their application efficiency as a water filtration membrane. The current review attempts to give a functionalist perspective of the fundamental progress in construction strategies of antibacterial and antiviral electrospun nanofibers. The review provides a list of antibacterial and antiviral agents commonly used as water membrane filters and discusses the challenges in the incorporation process. We have thoroughly studied the recent application of functionalized electrospun nanofibers in the water disinfection process, with an emphasis on their efficiency. Moreover, different antibacterial and antiviral assay techniques for membranes are discussed, the gaps and limitations are highlighted and promising strategies to overcome barriers are studies.
“…Then, the area of bacteria growth is detected, and the diameter of the inhibition zone around the electrospun nanofiber is measured. This procedure modifications are also used ( Santos et al, 2016 ; Wahab and Al Mamun, 2020 Fig.3 a). Fig.…”
Section: Antibacterial Performance Evaluation Of Electrospun Nanofibementioning
confidence: 99%
“… Fig. 3 a. Agar disc diffusion assay showing the clear zone of inhibition around electrospun polyacrylonitrile nanofiber mats containing titania/AgNP composite nanoparticles ( Wahab and Al Mamun, 2020 ); b. FESEM images of damaged E. coli on the single-walled carbon nanotubes-polyacrylonitrile/polyurethane/polyaniline electrospun nanofiber ( Xie et al, 2020 ); c. Photographs of colonies formed by B. subtilis and E. coli in water samples before and after electrospun coated nanofbrous polyacrylonitrile with polydopamine and silver nanoparticles (cPAN-Ag1.5) nanofbrous membranes ( Wang et al, 2017 ); d. Confocal Laser Scanning Microscopy (CLSM) images of cPAN-Ag1.5 nanofbrous membranes after filtration the bacteria suspension (green dots and red dots stands for live cells and dead cells, respectively) ( Wang et al, 2017 ). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)…”
Section: Antibacterial Performance Evaluation Of Electrospun Nanofibementioning
Pathogenic contamination has been considered as a significant worldwide water quality concern. Due to providing promising opportunities for the production of nanocomposite membranes with tailored porosity, adjustable pore size, and scaled-up ability of biomolecules incorporation, electrospinning has become the center of attention. This review intends to provide a detailed summary of the recent advances in the fabrication of antibacterial and antiviral electrospun nanofibers and discuss their application efficiency as a water filtration membrane. The current review attempts to give a functionalist perspective of the fundamental progress in construction strategies of antibacterial and antiviral electrospun nanofibers. The review provides a list of antibacterial and antiviral agents commonly used as water membrane filters and discusses the challenges in the incorporation process. We have thoroughly studied the recent application of functionalized electrospun nanofibers in the water disinfection process, with an emphasis on their efficiency. Moreover, different antibacterial and antiviral assay techniques for membranes are discussed, the gaps and limitations are highlighted and promising strategies to overcome barriers are studies.
“…The nanocomposites showed regular and bead-free nanofibers, and an increase in fiber diameter was observed when using nanoparticles. This has been interpreted as resulting from the localized agglomeration of nanoparticles within the fibers [71].…”
Section: • Functionalization Of Pan Fibersmentioning
confidence: 99%
“…The electrospinning process of PAN has been widely studied in the last few decades [12][13][14]18,[68][69][70][71][72][73]. The molecular weight of the most frequently used PAN is 150,000 g/mol.…”
Electrospinning is a simple and versatile method to generate nanofibers. Remarkable progress has been made in the development of the electrospinning process. The production of nanofibers is affected by many parameters, which influence the final material properties. Electrospun fibers have a wide range of applications, such as energy storage devices and biomedical scaffolds. Among polymers chosen for biological scaffolds, such as PLA or collagen, polyacrylonitrile (PAN) has received increasing interest in recent years due to its excellent characteristics, such as spinnability, biocompatibility, and commercial viability, opening the way to new applications in the biotechnological field. This paper provides an overview of the electrospinning process of a large range of polymers of interest for biomedical applications, including PLA and PEO. It covers the main parameters and operation modes that affect nanofiber fabrication. Their biological applications are reviewed. A focus is placed on PAN fiber formation, functionalization, and application as scaffolds to allow cell growth. Overall, nanofiber scaffolds appear to be powerful tools in medical applications that need controlled cell culture.
“…Another study by Jatoi et al developed electrospun polyacrylonitrile nanofibers containing AgNP-coated titanium dioxide. Antimicrobial tests against S. aureus and E. coli strains revealed that an increase in NP concentration led to enhanced antibacterial properties [ 163 ]. Additionally, Maharubin et al investigated the bactericidal effects of AgNPs covalently bonded on the surface of polyvinyl chloride films followed by the self-assembly of radiating acicular structured ZnO nanowires.…”
Section: Inorganic Nanoparticle-based Composite Films For Antimicrobial Applicationsmentioning
The development of drug-resistant microorganisms has become a critical issue for modern medicine and drug discovery and development with severe socio-economic and ecological implications. Since standard and conventional treatment options are generally inefficient, leading to infection persistence and spreading, novel strategies are fundamentally necessary in order to avoid serious global health problems. In this regard, both metal and metal oxide nanoparticles (NPs) demonstrated increased effectiveness as nanobiocides due to intrinsic antimicrobial properties and as nanocarriers for antimicrobial drugs. Among them, gold, silver, copper, zinc oxide, titanium oxide, magnesium oxide, and iron oxide NPs are the most preferred, owing to their proven antimicrobial mechanisms and bio/cytocompatibility. Furthermore, inorganic NPs can be incorporated or attached to organic/inorganic films, thus broadening their application within implant or catheter coatings and wound dressings. In this context, this paper aims to provide an up-to-date overview of the most recent studies investigating inorganic NPs and their integration into composite films designed for antimicrobial therapies.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
