Poly(methacrylic acid)‐Stabilized Silver Nanoclusters as Colorimetric Sensors for the Rapid and Sensitive Detection of Ascorbic Acid

Abstract

A simple, rapid, and sensitive colorimetric assay for ascorbic acid (AA) was developed based on poly(methacrylic acid)‐stabilized silver nanoclusters (PMAA‐AgNCs). The AgNCs were prepared via a single‐step synthesis exploiting PMAA as both a reducing agent and a stabilizer. The sensing capability of this method is based on the color change associated with the growth in size of AgNCs, which turn into nanoparticles, resulting from the reduction of free Ag+ present in AgNCs solution to Ag0 by AA. In the presence of AA, an apparent surface plasmon resonance absorption peak of the silver nanoparticles was observed at 430 nm, and its intensity increased linearly with AA concentration, so that a solution color change could be observed with the naked eye. The proposed method exhibited a linear working concentration range of 0.25–100 μM and a detection limit of 95 nM. The sensor was employed to determine AA concentration in fruit juice and vitamin C tablet samples, affording results of high accuracy.

Ascorbic Acid-Caused Quenching Effect of Protein Clusteroluminescence Probe: The Fast Fluorescent Detection of Ascorbic Acid in Vegetables

“…The redox titration method is simple to operate, but the determination of the titration endpoint is difficult to accurately achieve [23,25]. Although the operation of spectrophotometry has a simple detection process, the results are easily disturbed by the color of the sample itself [23,26]. The electrochemical techniques are sensitive, but cannot obtain accurate results in complex samples [23,27].…”

A Fluorescent Probe Based on Polyethyleneimine Protected Copper Nanoclusters for the Assay of Tetracycline Hydrochloride and Vitamin B12

“…The fluorescent probes have been known as the efficient tools to monitor amounts of chemical or biological matters due to simple sample pretreatment, fast response, small interference and high sensitivity. [21] In recent years, a new class of fluorescence materials, such as metal nanoclusters (MNCs) has been extensively employed to monitor various chemical or biological matters, [22] because MNCs have excellent chemical properties like small size, [23] long lifetime, [24] good photostability [25] and living cell compatibility. [26] Among fluorescent noble MNCs, silver and gold nanoclusters (AgNCs and AuNCs) were more widely studied fluorescence materials than the Cu nanoclusters (CuNCs).…”