Poly(hydroxybutyrate-co-hydroxyvalerate) microspheres loaded with atrazine herbicide: screening of conditions for preparation, physico-chemical characterization, and in vitro release studies

Lobo, Fabiana Aparecida; Aguirre, Carina Levy de; Silva, Mariana Santos; Grillo, Renato; Melo, Nathalie Ferreira Silva de; Oliveira, Liliam Karla de; Morais, Leandro Cardoso de; Campos, V.; Rosa, André Henrique; Fraceto, Leonardo Fernandes

doi:10.1007/s00289-011-0447-6

Cited by 46 publications

(40 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The efficiency decreased as the proportion of PHBV decreased, and formulation E (100 % PHB) provided the lowest encapsulation efficiency (26.2 %). The values obtained for formulations A and B were fairly high, relative to values that have been reported in the literature for other active principles (Bazzo et al, 2009;Grillo et al, 2010;Lobo et al, 2011;Sendil et al, 1999). Grillo and colleagues (2010) showed that the encapsulation efficiency of the herbicide atrazine in PHBV microparticles was in excess of 30 %.…”

Section: Resultsmentioning

confidence: 65%

“…Microparticles were prepared with the PHB and PHBV polymers, used either individually or as a mixture, by formation of oil in water emulsions using the emulsification-solvent evaporation technique (Coimbra et al, 2008;Conti et al, 1995;Lionzo et al, 2007;Lobo et al, 2011). 200 mg of polymer (PHB, PHBV or a mixture of the two polymers, as described in Table 1) and 10 mg of herbicide were dissolved in 10 mL of chloroform to form the organic phase.…”

Section: Preparation Of the Polymeric Microparticles Containing Ametrynmentioning

confidence: 99%

“…Several studies have investigated controlled-release systems for bioactive compounds in agricultural applications (Ahmadi & Ahmadi, 2007;Bin Hussein et al, 2010;El Bahri & Taverdet, 2005Grillo et al, 2010;Hirech et al, 2003;Li et al, 2010;Lobo et al, 2011;Silva et al, 2010;Singh et al, 2008Singh et al, , 2010. Materials that have been used include silica, bentonite and sepiolite clays, and polymeric substances such as alginate, lignin and synthetic polymers.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Preparation and Characterization of Polymeric Microparticles Used for Controlled Release of Ametryn Herbicide

Lobo¹,

Aguirre²,

Souza³

et al. 2012

Herbicides - Properties, Synthesis and Control of Weeds

Self Cite

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 65%

Section: Preparation Of the Polymeric Microparticles Containing Ametrynmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Preparation and Characterization of Polymeric Microparticles Used for Controlled Release of Ametryn Herbicide

Lobo¹,

Aguirre²,

Souza³

et al. 2012

Herbicides - Properties, Synthesis and Control of Weeds

Self Cite

View full text Add to dashboard Cite

“…Um deles é o cálculo da taxa de encapsulamento dos nutrientes na matriz polimérica, como também a concentração de nutriente que este sistema libera no decorrer de um determinado tempo. [6][7][8][9][10][11][12][13][14][15][16][17][18] Assim, são requeridas técnicas analíticas para a quantificação da concentração dos cátions metálicos nesses processos.…”

Section: Introductionunclassified

Otimização multivariada de metodologia para digestão de micropartículas poliméricas carreadoras de cátions metálicos

et al. 2016

Self Cite

View full text Add to dashboard Cite

Recebido em 28/03/2016, aceito em 06/07/2016, publicado na web em 16/08/2016 MULTIVARIATE OPTIMIZATION OF METHODOLOGY FOR POLYMERIC MICROPARTICLE DIGESTION METALLIC CATION CARRIERS. There are not reports in the literature of digestion processes of metallic cation carrier microparticles. Multivariate experimental designs were utilized to ensure an appropriate digestion for further analysis by atomic absorption spectroscopy. It was used a heater plate and the polimeric degradation was evaluated utilizing an analyzer of total organic carbon (TOC). For the total carbon (TC) content, the full factorial design 2 4 pointed the significance of sample volume (V Am ), in relation to the variables acid volume (V Ac ), temperature (T) and digestion time (t). However, according to the normal distribution graph it was noted a possible significance of the T and t effects. The same was observed for TOC, including the V Am × V Ac × T effect suggestive of complex behavior. In the central composite design all variables were again studied and the V AM was significant, promoting a TC decreasing at the lower evaluated level. By ANOVA a quadratic model without lack of fit was found, with the significant quadratic term. The best digestion condition was: 5.00 mL of sample, 10.00 mL of nitric acid, 60 ºC and 90 min. The multivariate optimization allowed an efficient digestion, with the initial carbon concentration of 4.60 mg L -1 decreased to 0.55 mg L -1 .Keywords: metallic cations; polymeric microparticles; sample preparation; digestion; multivariate experimental designs. INTRODUÇÃOOs cátions metálicos são parte essencial dos fertilizantes, pois eles são responsáveis por várias funções nas plantas, que vão desde a participação na síntese de proteínas, até sua presença em enzimas que participam de processos da fotossíntese. 1-2 Fertilizantes ou adubos são compostos químicos inorgânicos ou orgânicos utilizados para propiciar os nutrientes essenciais ao desenvolvimento das plantas, e são aplicados na agricultura para um maior rendimento da produção. 3 No entanto, atualmente, estudos 4-5 demonstram que para a maioria dos fertilizantes usados, parte dos seus nutrientes são perdidos no ambiente, podendo ocasionar uma série de contaminações ambientais. Por exemplo, os fertilizantes que possuem em sua composição nitratos e fosfatos podem perder parte desses compostos em processos de lixiviação, propiciando o processo de eutrofização em águas de mananciais e lençóis freáticos. Ainda, os fertilizantes quando não aplicados de forma correta podem proporcionar desequilíbrios no ecossistema e aumento do número das fontes de toxicidade aguda e carcinogênicas para os seres humanos. [4][5] Desta forma, o uso adequado dos fertilizantes é uma atividade que deve ser levada em consideração, visando à sustentabilidade econômica, ambiental e social do agronegócio mundial.Nos últimos anos a tecnologia de liberação controlada/modificada tem ganhado destaque, pois ela emergiu como uma importante alternativa capaz de resolver alguns dos problemas que acompanham ...

show abstract

“…Many different types of materials, including drugs [6], proteins [7,8], food materials [9,10], pesticides [11] and herbicides [12], as well as cells [13,14] can be encapsulated.…”

Section: Definition and General Featuresmentioning

confidence: 99%

Designing polymeric microparticles for biomedical and industrial applications

Campos

Branquinho

Carreira

et al. 2013

European Polymer Journal

155

View full text Add to dashboard Cite

Poly(hydroxybutyrate-co-hydroxyvalerate) microspheres loaded with atrazine herbicide: screening of conditions for preparation, physico-chemical characterization, and in vitro release studies

Cited by 46 publications

References 43 publications

Preparation and Characterization of Polymeric Microparticles Used for Controlled Release of Ametryn Herbicide

Preparation and Characterization of Polymeric Microparticles Used for Controlled Release of Ametryn Herbicide

Otimização multivariada de metodologia para digestão de micropartículas poliméricas carreadoras de cátions metálicos

Designing polymeric microparticles for biomedical and industrial applications

Contact Info

Product

Resources

About