Polimorfismos en los genes dihidrofolatorreductasa (dhfr) y dihidropteroatosintetasa (dhps) y modelamiento estructural del gen dhps en aislamientos colombianos de Toxoplasma gondii

Cortés, Liliana Jazmín; Duque, Sofía; López, Miryam Consuelo; Moncada, Diego; Molina, Diego; Gómez‐Marín, Jorge Enrique; Gunturiz, María Luz

doi:10.7705/biomedica.v34i4.2132

Cited by 4 publications

(2 citation statements)

References 28 publications

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“…Immunohistochemical markers were used in tissue from both fetuses. Molecular testing for syphilis, toxoplasmosis, rubella, and cytomegalovirus was performed following techniques described previously ( 9 , 10 ); 500-band resolution karyotype was also performed for both fetuses, and ELISA testing for HIV was performed on maternal serum samples.…”

Section: The Casesmentioning

confidence: 99%

Severe Neurologic Disorders in 2 Fetuses with Zika Virus Infection, Colombia

Acosta‐Reyes¹,

Navarro²,

Herrera³

et al. 2017

Emerg. Infect. Dis.

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Section: The Casesmentioning

confidence: 99%

Severe Neurologic Disorders in 2 Fetuses with Zika Virus Infection, Colombia

Acosta‐Reyes¹,

Navarro²,

Herrera³

et al. 2017

Emerg. Infect. Dis.

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“…The patient may have developed severe disease despite co-trimoxazole prophylaxis due to resistance to sulfonamide (12,13). In this sense, more-virulent Toxoplasma strains have been found in Colombia and transmission of toxoplasmosis by renal transplant was reported in two local cases (14,15).…”

Section: Discussionmentioning

confidence: 99%

Disseminated toxoplasmosis in a heart transplant patient despite co-trimoxazole prophylaxis: A case report

Dávila¹,

Roncancio-Villamil

Correa

et al. 2017

biomedica

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We report the case of a 61 year-old male who underwent heart transplantation eight months before developing a systemic condition with central nervous system, lung, kidney, colonic, cutaneous, and hematologic involvement, found to be secondary to a systemic toxoplasmosis despite co-trimoxazole prophylaxis in a previous-to-transplant seronegative patient receiving a heart from a seropositive donor. A review of prophylactic options in our environment is discussed.Key words: Toxoplasmosis; heart transplantation; immune tolerance; seroconversion. doi: https://doi.org/10.7705/biomedica.v34i2.3189Toxoplasmosis diseminada en un paciente con trasplante de corazón a pesar de la profilaxis con trimetoprim-sulfametoxazol Se reporta el caso de un paciente de sexo masculino, de 61 años de edad, quien ocho meses después de someterse a un trasplante de corazón presentó una enfermedad sistémica con compromiso del sistema nervioso central y del sistema inmunológico, así como de pulmón, riñón, colon y piel, y a quien finalmente se le diagnosticó toxoplasmosis diseminada, a pesar de haber recibido profilaxis con trimetoprim-sulfametoxazol, debido a que el órgano provenía de un donante positivo para toxoplasmosis siendo él un receptor negativo. Se discuten las opciones de profilaxis en nuestro medio.Palabras clave: toxoplasmosis; trasplante de corazón; tolerancia inmunológica; seroconversión.

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