Polarographic behaviour of isatin and some of its derivatives in DMF

Enantioselective reduction of isatin derivatives over cinchonidine modified Pt/alumina

“…Hence, we conclude that the isatide does not decompose but reacts back to reactant and alcohol. Such a disproportionation was reported by Romanin and coworkers [43] for dimer 9 in DMF. Since the forward reaction (isatide formation from alcohol and reactant) is catalyzed by CD, the disproportionation has to be CD catalyzed as well.…”

Electrochemical behaviour of isatin at a glassy carbon electrode

“…The cathodic peak 3 c , E pc = −0.48 V, appears to be due to the reduction of the carbonyl group at position 3 of the isatin moiety [16]. On the other hand, it is known that in acidic media, isatin is reduced in a 1-electron step giving rise to a radical that can react with an isatin molecule leading to the formation of the dimer isatide [16].…”

“…On the other hand, it is known that in acidic media, isatin is reduced in a 1-electron step giving rise to a radical that can react with an isatin molecule leading to the formation of the dimer isatide [16]. Therefore, the cathodic peak 4 c at E pc = −0.59 V could be due to the reduction of isatide, formed at the electrode surface after reduction of isatin, as shown in the proposed reduction mechanism (Scheme 3).…”

“…Although the presence of two carbonyl groups in isatin makes it an attractive target to synthetic organic chemists, little is known about its redox mechanism. Previous studies on the electrochemical reduction behavior of isatin and analog compounds have been undertaken using polarography at mercury electrodes [16][17][18][19]. Although Scheme 1.…”

Electrochemical Reduction of Isatin-monohydrazone on Mercury Electrode

“…10 Hydrazones and their metal complexes attracted much attention because of their medicinal, physicochemical properties and applications in many important chemical processes. [11][12][13][14] The electrochemical behaviors of isatin and some of its derivatives 9,[15][16][17][18][19][20][21] were examined. The knowledge of the redox properties of hydrazone compounds is important for a better understanding of their behaviors in both chemical and biological processes.…”