Polarographic behaviour of biotin

Serna, A.; Vera, Juan B.; Marín, Dolores Pérez

doi:10.1016/s0022-0728(73)80018-x

Cited by 11 publications

(4 citation statements)

References 6 publications

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“…One electron is transferred in the complete reduction of biotin. Further evidence of a one electron reduction was reported by Serna et al 95 and Pitre et al 5 Cyclic voltammetric data are shown in Figure 13 for biotin in DMF at a platinum disk. The Ag|AgCl miniature reference electrode used in DMF does not provide a true reference; potentials are reported relative to an internal ferrocene reference (Fc|Fc + ).…”

Section: Vitamin B7 -Biotinsupporting

confidence: 59%

Critical Review—Electrochemical Properties of 13 Vitamins: A Critical Review and Assessment

Lovander

Lyon

Parr

et al. 2018

J. Electrochem. Soc.

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Review of the literature on the currently recognized, thirteen vitamins yields an overview of the electrochemical properties that include estimates of the formal potentials at physiological pH and identification of the general classes of redox mechanisms. All vitamins are electroactive and map a range of formal potentials E 0 over a 3 V window. The vitamins are grouped as lipid soluble (vitamins A, D, E, and K) and water soluble (B vitamins and vitamin C). Mechanisms are grouped as single electron transfer agents (B3, B7, B2, C, and D), vitamins that can be both oxidized and reduced (B1, B5, B6, B9, and E), and vitamins that undergo two successive, distinct reductions (B12 and K). Vitamin A voltammetry is uniquely complex. Plot of the formal potentials on a potential axis allows assessment of mechanistic paths to vitamin recycling, antioxidant behavior, pH dependence, electrochemical stability in air, acid, and water, electrochemical instability of vitamin pairs, and cooperative interactions between vitamins in medicine. The potential axis is shown as an effective tool for mapping thermodynamically complex interactions. By modern standards, the US federal government identifies 13 vitamins.3 The water soluble vitamins are vitamin C and the eight B vitamins (B1, B2, B3, B5, B6, B7, B9, B12). The lipid or fat soluble vitamins are A, D, E, and K. The fat soluble vitamins can accumulate in the body whereas the water soluble vitamins do not. There are no current vitamins designated beyond E except for K because materials historically assigned the interposed letter designations either no longer fall under the modern definition of vitamin or several related materials were reclassified. Several vitamins exist in different but related chemical structures.Questions considered in this perspective include whether all vitamins are electroactive; what is the redox potential of the vitamins; what are the kinetics and mechanisms of vitamins on oxidation and reduction; when are vitamins antioxidants; are vitamins stable to water and oxygen; do vitamins interact cooperatively. Although papers are available on the electrochemistry and voltammetry of individual vitamins, no single resource summarizes the electrochemical data for all vitamins. This review compiles and critically assesses the available literature on vitamin voltammetry. The compiled data serve to develop perspective on the electrochemical properties of vitamins and the role of vitamins individually and collectively as electroactive species. This CRES 3 T review assimilates fundamentals of thermodynamics and estimated formal potentials, kinetics, and mechanisms as assessed voltammetrically for individual vitamins to provide perspective on the collective electrochemical properties of the thirteen vitamins. Perspective on vitamin electrochemical properties may contribute to assess yet more complex bioelectrochemical processes. * Electrochemical Society Student Member.* * Electrochemical Society Fellow. z E-mail: johna-leddy@uiowa.eduThe review contains two main sections....

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Section: Vitamin B7 -Biotinsupporting

confidence: 59%

Critical Review—Electrochemical Properties of 13 Vitamins: A Critical Review and Assessment

Lovander

Lyon

Parr

et al. 2018

J. Electrochem. Soc.

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“…Procedures for the polarographic determination of riboflavine in fermentation broths (11), urea in process streams (103), activity of BCG Vaccine (1157), of catecholamines in biological tissue (148), amino acid-p-nitroanilides (190), biotin (987) and some of its intermediates (251), oxygen in blood (370), d-glucuronolactone (1078), and pectins (1014) were reported. The charge and presence of active groups on the surface of whole sperm cells were detected (1144).…”

Section: Biological-pharmaceutical Studiesmentioning

confidence: 99%

Organic polarography

Pietrzyk¹

1974

Anal. Chem.

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Chemical Titles, and readily available journals ending November 30, 1973. This period has seen a continued growth in the use of polarography and related electrochemical techniques to follow chemical reactions and to supplement other physical and spectral measurements for purposes of characterization. Interest in applications toward biochemical and pharmaceutical problems has also increased. There also appears to be renewed interest in utilizing polarographic and related electrochemical data to predict and follow organoelectrochemical synthesis.In this review the symbols cv, dc, ac, and op are used to identify cyclic voltammetry, direct current polarography, alternating current polarography, and oscillographic polarography, respectively. Also, no attempt was made to list all organic polarographic references.

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“…Pioneering work, dating back over 40 years, unravels an irreversible one-electron reduction of biotin at −1.8 V, in dimethylformamide (DMF)−water solutions. 11,12 The topic was revisited by Lauw et al to investigate biotin reduction at a platinum (Pt) surface, in DMF and dimethylsulfoxide (DMSO) supported by the organic salt tetrabutylammonium hexafluorophosphate (TBAPF). 13 Therein, biotin at 2 mM is reduced by one-electron to form a carboxylate anion and dihydrogen in DMF and DMSO.…”

Section: ■ Introductionmentioning

confidence: 99%

“…16 Recent reports have demonstrated its applicability for detection of Pseudomonas quinolone signal, 2-heptyl-4-hydroxyquinoline, pyocyanin, 17−19 2-(2-hydroxyphenyl)-thiazole-4-carbaldehyde (IQS), 20 and barakacin 21 as a molecular signature of Pseudomonas aeruginosa. There are a number of analytical techniques reported for biotin determination such as spectrometry, 22 polarography, 12 thin-layer chromatography, 23 capillary electrophoresis, 24 and high-performance liquid chromatography. 25−27 This communication unravels a new strategy for specific analysis of biotin based on its electrochemical oxidation of biotin at the surface of a Nafion-modified BDD electrode in an aqueous media.…”

Section: ■ Introductionmentioning

confidence: 99%