Poksvirüs İle Doğal Enfekte Koyunlarda, Bazı Akut Faz Proteinler, Biyokimyasal Parametreler ve Oksidatif Stresin Belirlenmesi

Bozukluhan, Kadir; Merhan, Oğuz; Gokce, H. I.; Öğün, Metin; Atakişi, Emine; Kiziltepe, Şemistan; Gökçe, Gürbüz

doi:10.9775/kvfd.2017.19167

Cited by 7 publications

(14 citation statements)

References 23 publications

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“…There are also situations in which increase was detected in SOD and GPx activity with oxidants such as MDA, H 2 O 2 and decrease in CAT activity [88] . In sheep infected with sheeppox virus, an increase was found in MDA, while a decrease was found in GSH and albumin [89] . This decrease in albumin results from suppression of the antioxidative system and negative acute phase reactant due to infection.…”

Section: Oxidative Stress In Viral Infectionsmentioning

confidence: 93%

Enfektif Hastalıklarda Oksidan ve Antioksidan Parametrelerin Rolü: Sistematik Bir Literatür Değerlendirmesi

Çenesiz¹

2020

Kafkas Univ Vet Fak Derg

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The formation of reactive oxygen species is a physiological event in aerobic life. In case of infection, if the increased oxidant substances cannot be cleaned sufficiently by antioxidants, oxidative stress occurs. As a result, a number of pathological problems occur by damaging DNA, protein, carbohydrate and lipids. In biological systems, the balance between oxidants and antioxidants is important. In oxidative stress situations where the balance cannot be achieved sufficiently, support can be provided with the use of exogenous antioxidants. However, the molecular structure, route of administration and concentrations of these exogenous antioxidants are important. Otherwise, they may show a pro-oxidative effect. The present rewiev study makes a general overview of oxidative-nitrosative stress markers commonly used in infective clinical studies, antioxidant enzymes and parameters and antioxidant supplements.

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Section: Oxidative Stress In Viral Infectionsmentioning

confidence: 93%

Enfektif Hastalıklarda Oksidan ve Antioksidan Parametrelerin Rolü: Sistematik Bir Literatür Değerlendirmesi

Çenesiz¹

2020

Kafkas Univ Vet Fak Derg

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“…19 Although there are limited studies in calves, a study conducted in calves with enzootic pneumonia reported that vitamin D concentrations were decreased in diseased animals. 4 What we do know is that vitamin D concentrations are lower in calves from birth until they are 3 months old that serum vitamin D concentrations may not increase despite vitamin supplementation during this early age, and that there is a lack in the development of immunity, making these young animals prone to lung diseases. 13 Accordingly, it has been suggested that serum vitamin D concentrations should be measured in young calves.…”

Section: Variablesmentioning

confidence: 99%

“…In addition to these physical and environmental factors, various bacteria, viruses, and other infectious agents are found alone or together in the etiology of this disease. 2 The diagnosis of enzootic pneumonia is based on clinical findings seen most often in 2-to 6-month-old calves [2][3][4] ; manifestations include cough, breathing difficulties, varying degrees of fever, and nasal discharge, which are sufficient for clinical diagnosis. Deep nasal swabs and swabs of ocular discharge are recommended for the detection of viral pathogens, whereas transtracheal aspiration and bronchoalveolar lavages are recommended for the detection of bacterial and mycoplasma pathogens.…”

Section: Introductionmentioning

confidence: 99%

“…3 And, if enzootic pneumonia is not controlled, complications may occur due to multi-organ failure and increased mortality. 4 Vitamin D, which is involved in the mineralization of the skeletal system in animals, is a fat-soluble steroid vitamin. 5 It is important in bone development, immune system regulation, cellular proliferation and differentiation, neurologic and cardiovascular systems, and prevention of infectious diseases.…”

Section: Introductionmentioning

confidence: 99%

“…Another study on enzootic pneumonia stated that vitamin D decreased due to the disease and its severity, and therefore, vitamin D supplementation is important in the treatment and prevention of infection. 4 This study determined serum vitamin D concentrations in healthy calves and calves with enzootic pneumonia in the same age groups and environmental and care-feeding conditions. We also aimed to determine the relationship between serum vitamin D status and the severity of enzootic pneumonia.…”

Section: Introductionmentioning

confidence: 99%

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Serum vitamin D3 (25‐OH vit D3) concentrations and hemogram changes in calves with enzootic pneumonia

Ertunç,

Mecitoğlu,

Kasap

et al. 2024

Veterinary Clinical Pathol

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BackgroundEnzootic pneumonia is an important disease complex associated with insufficient colostrum intake after birth, adverse environmental conditions, and stress. Vitamin D deficiency may be an important predisposing factor for this disease.ObjectiveThis study aimed to investigate in calves with enzootic pneumonia.MethodsA total of 30 calves, aged 3–5 months, under the same care and feeding conditions were used. Groups were formed according to Clinical Respiratory Scoring as the group with mild/moderate enzootic pneumonia (n = 10), the group with severe enzootic pneumonia (n = 10), and the healthy control group (n = 10) without any disease. Blood samples were collected from the jugular vein of animals in all groups on Day 0; a complete blood count was performed, and serum vitamin D levels were measured using the Liquid Chromatography–Tandem Mass Spectrometry (LC–MS/MS) method.ResultsAlthough no statistical differences were observed in total leukocyte, lymphocyte, eosinophil, basophil, hemoglobin, and hematocrit levels between groups, statistically significant differences in blood neutrophil, monocyte, and erythrocyte counts were found between the groups. Monocyte counts were statistically decreased in the mild/moderate group compared with the control group. Neutrophil counts were significantly higher in the mild/moderate and severe groups than in the control group. Erythrocyte counts were increased in the mild/moderate and severe groups compared with the control group. Vitamin D concentrations were statistically lower in the mild/moderate and severe groups than in the control group. However, no statistical differences in Vitamin D concentrations were observed between the mild/moderate and severe groups. There was a negative and significant correlation between erythrocyte counts and vitamin D concentrations (r = −0.64, P < .0001). While erythrocyte counts increased in the severe group compared with the mild/moderate group, vitamin D concentrations decreased. Also, a negative and significant correlation was observed between platelet counts and vitamin D concentrations (r = −0.74, P < .0001).ConclusionsThe results of this study determined that serum vitamin D concentrations in calves with pneumonia were lower than those in healthy calves. Detailed studies on the etiologic and prognostic importance of low vitamin D levels in calves with enzootic pneumonia may provide valuable data for prevention and treatment.

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Investigation of Aopp, Total Sulphydryl Group (T-sh), Seroplasmin Levels in Sheep Wi̇th Zoonotic Liver Parasitosis

OĞUZ,

KÖMÜROĞLU,

AYAN

et al. 2024

Preprint

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The aim of inthe present study was to investigate aopp, total sulfhydryl group (t-sh) and seroplasmin levels in zoonotic liver parasitosis in sheep. this study was carried out in Iğdır province. For this purpose, 75 sheep were grouped as healthy, Fasciola spp., Echinococcus spp., Dicrocoelium spp., Echinococcus spp. + Dicrocoelium spp. The levels of the specified parameters were measured in these groups. According to the results, AOPP level in the fasciolosis group was remarkably higher than all other groups (p < 0.05). The serum AOPP level in the E + D group was found to be significantly higher compared to the control and dicrocoelium spp. groups (p < 0.05). Echinococcus spp. group was s remarkably higher than the dicrocoelium spp. group (p < 0.05). The ceruloplasmin level in the control group was found to be significantly lower compared to the Echinococcosis, fasciolosis and dicrocoeliosis groups (p < 0.05). Total sulfhydryl level was found to be lower in the patient groups compared to the healthy group, but this value was not significant. According to these results, it can be said that cellular damage occurs in liver parasitism. These parameters are thought to be valuable in terms of prognosis in parasitic infections. It is also thought that oxidative cell damage occurs in the attack of zoonotic liver parasites in which the immune response decreases. It is thought that this study will serve as a guide for future research.

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Poksvirüs İle Doğal Enfekte Koyunlarda, Bazı Akut Faz Proteinler, Biyokimyasal Parametreler ve Oksidatif Stresin Belirlenmesi

Cited by 7 publications

References 23 publications

Enfektif Hastalıklarda Oksidan ve Antioksidan Parametrelerin Rolü: Sistematik Bir Literatür Değerlendirmesi

Enfektif Hastalıklarda Oksidan ve Antioksidan Parametrelerin Rolü: Sistematik Bir Literatür Değerlendirmesi

Serum vitamin D3 (25‐OH vit D3) concentrations and hemogram changes in calves with enzootic pneumonia

Investigation of Aopp, Total Sulphydryl Group (T-sh), Seroplasmin Levels in Sheep Wi̇th Zoonotic Liver Parasitosis

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