Spontaneous pneumomediastinum has been reported as a rare complication in COVID-19 pneumonia. Symptoms in pneumomediastinum are usually nonspecific. A 36-yearold male patient was admitted to our clinic with shortness of breath, cough, and left flank pain. His computed tomographic (CT) examination of the thorax showed pneumomediastinum. The patient was accepted as COVID-19 pneumonia and related pneumomediastinum. This case was presented to emphasize that patients with severe Covid-19 pneumonia on computed tomography may develop pneumomediastinum during treatment.