2013
DOI: 10.1590/s0102-86502013000600003
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Pneumoperitoneum induces morphological alterations in the rat testicle

Abstract: PURPOSE:To investigate the seminiferous tubule histological morphology after an 8 mmHg pneumoperitoneum in the rat model. METHODS:Fourteen rats were divided into two groups: a Sham group submitted to anesthesia and a pneumoperitoneum (Pp) group submitted to abdominal insufflation at 8 mmHg during three hours, followed by desuflation. All rats were killed after six weeks, testicles were collected and evaluated for the tubule diameter, germinative epithelium height and Johnsen´s score. Means were compared by usi… Show more

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Cited by 7 publications
(13 citation statements)
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“…The diameter was considered the mean of 3 measurements taken on each tubule. Furthermore, the seminiferous epithelium height was calculated as the mean of 3 measurements on 125 tubules per animal by using the ImageJ software under x200 magnification 19 .…”
Section: Morphological Evaluationmentioning
confidence: 99%
“…The diameter was considered the mean of 3 measurements taken on each tubule. Furthermore, the seminiferous epithelium height was calculated as the mean of 3 measurements on 125 tubules per animal by using the ImageJ software under x200 magnification 19 .…”
Section: Morphological Evaluationmentioning
confidence: 99%
“…Testicular tissue changes we're not observed in short (Aydin et al, 2014) and long-term (Ribeiro et al, 2013) at pressures equal to, or lower than 8 mmHg. A pressure of 6 mmHg may be insufficient to perform minimally invasive procedures in small animals, where an IAP between 8 and 12 mmHg is usually used.…”
Section: Resultsmentioning
confidence: 52%
“…This is even lower than the 15 mmHg pressure used in humans due to the thinness of the abdominal wall (Brun, 2015), resulting in greater compliance. The absence of changes in Johnsen scores in samples collected after 6 weeks of exposure to pneumoperitoneum (Ribeiro et al, 2013) may be indicative of germ cell restocking in the seminiferous tubules after injury since the mouse spermatogenic cycle is 48 to 52 days (De Kretser, 1982), rather than of injuries. Ribeiro et al (2013) analyzed long-term studies and differed from Istanbulluoglu et al (2011) because their study not show testicular lesions.…”
Section: Resultsmentioning
confidence: 99%
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