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Cited by 84 publications
(46 citation statements)
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“…An elevated, >0.5 ng . mL -1 serum PCT level was found in over half of PNC pneumonia cases, in agreement with previous studies on bacterial pneumonia [14,15]. On the other hand, that limit was exceeded as often as in one third of viral pneumonia cases.…”
Section: Discussionsupporting
confidence: 92%
“…An elevated, >0.5 ng . mL -1 serum PCT level was found in over half of PNC pneumonia cases, in agreement with previous studies on bacterial pneumonia [14,15]. On the other hand, that limit was exceeded as often as in one third of viral pneumonia cases.…”
Section: Discussionsupporting
confidence: 92%
“…Previously, increases in serum calcitonin-like reactivities were found in patients with infections [14] or with lung disease [11,12]. However, the methods employed did not discriminate between calcitonin and procalcitonin although some of the "calcitonin-like activity" in these studies may well be attributable to increases in procalcitonin levels.…”
Section: Measurement Of Procalcitoninmentioning
confidence: 65%
“…Thus, patients who have previously undergone a total thyroidectomy can still produce high levels of procalcitonin during a severe infectious episode [9]. The exact site of procalcitonin production during sepsis is uncertain; one investigator, using katacalcin antibodies, has identified procalcitonin-like activity in human leukocytes [10], others suggest neuroendocrine cells and the lungs [11][12][13] as possible sites of production. Remarkably, the large amounts of procalcitonin produced during infections do not lead to an increase in plasma calcitonin levels or activity [9].…”
Section: Physiology Of Procalcitoninmentioning
confidence: 99%
“…In the PCT group, the physician was advised to follow the antibiotic treatment algorithm based on the PCT value and the likelihood of bacterial disease [1,12,58,59]. In four now completed intervention trials enrolling .1,200 patients, the success of the intervention was measured by clinical outcomes, assuming that if the patient recovered without antibiotics then there was no serious bacterial illness [60][61][62][63].…”
Section: Pct For Antibiotic Stewardship Of Respiratory Tract Infectionsmentioning
confidence: 99%