Pneumonectomy for Non-Small Cell Lung Cancer: Predictors of Early Mortality and Morbidity

Diabetes Mellitus and Risk of Bronchopleural Fistula After Pulmonary Resections: A Meta-Analysis

“…Then, 18 of them were considered for possible eligibility for quantitative synthesis [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34]. Finally, a total of 15 studies met the eligibility criteria and were included in our meta-analysis [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]. The other three studies were finally excluded because details of DM and BPF formation were incomplete [32][33][34].…”

“…The basic characteristics of the 15 studies are summarized in Table 1. All of them were retrospective observational studies [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]. More than half of these studies (n ¼ 8) were conducted in Asian countries, including four in Japan [17,19,27,29], two in China [20,31], one in Korea [25], and one in Turkey [30].…”

“…None of the enrolled patients was lost during follow-up. However, only three studies [17,20,28] provided the adjusted outcomes by adequately eliminating the major confounders that were not completely consistent. The relevant results are summarized in Table 2 and the Appendix, "Quality levels of the included studies.…”

“…All of these eight studies used univariate analysis to identify some possible parameters among all the analyzed variables at first and then multivariate analysis to adjust for confounding factors and clarify the statistical significance of these possible parameters. However, only three studies published the adjusted results of multivariate analysis, including the OR with 95% CI in one study [28] and the b value with corresponding SE in two studies [17,20]. In this metaanalysis, the majority of the OR outcomes were extrapolated from the demographic data based on univariate analysis [19,[21][22][23][24][25][26][27][29][30][31].…”

Pneumonectomy for Non–Small Cell Lung Cancer

“…50,51 Consequently, for right pneumonectomy, postoperative management is crucial. As on the left side, a muscle-sparing posterolateral thoracotomy skin incision is made.…”