Pneumococcal endocarditis

Ruegsegger, James M.

doi:10.1016/0002-8703(58)90195-9

Cited by 17 publications

(9 citation statements)

References 66 publications

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“…Prior to the advent of penicillin, the pneumococcus was a more frequent cause of IE than the staphylococcus. (289) When the disease was common, it was usually discovered during the course of pneumococcal pneumonia and frequently caused destruction of the aortic valve. Interestingly, type III pneumococcus, which commonly caused pneumonia, rarely caused IE, the reverse being true for types VII and XII.…”

Section: Pneumococcimentioning

confidence: 99%

“…Interestingly, type III pneumococcus, which commonly caused pneumonia, rarely caused IE, the reverse being true for types VII and XII. (289) In series of IE recently described, the pneumococcus was considered responsible for 3% of cases in 308 blood-culture-positive, non-prosthetic-valve patients. (78.153-155.290) The disease is rarely seen in infants despite the common finding (2.6%) of pneumococcal bacteremia in febrile infants seen in a walk-in clinic.…”

Section: Pneumococcimentioning

confidence: 99%

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Infective Endocarditis and Other Intravascular Infections

Freedman¹

1982

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Section: Pneumococcimentioning

confidence: 99%

Section: Pneumococcimentioning

confidence: 99%

Infective Endocarditis and Other Intravascular Infections

Freedman¹

1982

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“…The most consistent clinical features in our small series were unexplained fever and rapidly progressive congestive heart failure, despite appropriate antimicrobial treatment and most commonly due to severe aortic valve insufficiency. At presentation, however, a regurgitant murmur was not always heard, an observation also made by others [22][23][24]. One patient manifested a major vascular embolic phenomenon.…”

Section: G a W Bruyn And Othersmentioning

confidence: 60%

Pneumococcal Endocarditis in Adult Patients. A Report of Five Cases and Review of the Literature

Bruyn

Thompson

Meer

1990

QJM: An International Journal of Medicine

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A retrospective survey of patients with pneumococcal infective endocarditis at the University H ospital, Leiden, over a 10-year period (1976-1986) yielded five cases. Applying strict case definitions, four patients had definite and one patient possible pneumococcal endocarditis. The commonest presenting signs and symptoms were malaise, fever, and congestive heart failure. Predisposing conditions were previous splenectomy in one case and a valve prosthesis in another. The aortic valve was the most common site o f infection, in four o f the five patients the diagnosis o f endocarditis was made during life. These patients were treated appropriately, i.e. with antibiotics to which S. pneum oniae is sensitive. In three patients, surgical intervention was performed in the acute phase because of progressive heart failure. Paravalvular abscesses were observed at surgery in all these cases. The four patients treated in our series recovered fully; the single fatal case constituted an unrecognized case of pneumococcal endocarditis. If recognized and treated appropriately (particularly with early selective surgery) endocarditis can be cured. In a statistical analysis o f 36 patients with pneumococcal endocarditis reported during the past five years, we found a significantly higher occurrence and mortality in men than in women; no other clinical features were associated with a poor outcome o f illness. IN T R O D U C T IO NInfective endocarditis due to Streptococcus pneumoniae was a lethal condition before the availability of penicillin. Usually it was a complication of lobar pneumonia and its incidence among cases of lobar pneumonia ranged between 1 and 5 per cent [1][2][3]. The incidence of pneumococcal endocarditis among all cases of infective endocarditis varied between 12 and 25 per cent [4][5][6]. The incidence of pneumococcal endocarditis has declined to less than 5 per cent since penicillin became available [7][8][9], whereas the incidence of pneumococcal bacteraemia remained stable. Recent studies have shown that outcomes in pneumococcal To determine current clinical features and outcome of patients with pneumococcal endocarditis, we made a retrospective analysis of patients with this diagnosis admitted to the University Hospital Leiden from January 1976 to January 1986. PATIENTS AND METHODSAll records of patients older than 15 years of age, admitted to University Hospital Leiden (a 900-bed hospital with both referral and primary patient populations) from 1 January, 1976, to 1 January, 1986, with pneumococcal bacteraemia were reviewed. These included five cases in which the diagnosis of pneumococcal endocarditis was made clinically. Records of patients listed in the Department of Pathology as having infective endocarditis were also reviewed, yielding one additional case in which pneumococcal endocarditis was first discovered at autopsy. For the diagnosis of pneumococcal infective endocarditis the criteria as defined by Von Reyn et al. [14] were used. Only definite, probable, or possible episodes were included in thi...

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“…Whether a damaged valve is a predisposing factor remains unclear. Clinical signs of valvu-lar or rheumatic heart disease is seen among less than 10% (12). Some studies of autopsies from 1945 to 1965 have shown predisposing heart disease (mainly rheumatic) among 40-66% of patients who died due to PE (13), but other studies were not able to confirm this finding (14,15).…”

Section: Discussionmentioning

confidence: 98%

Recurrent Endocarditis Caused by Streptococcus pneumoniae

Lindberg

Fangel²

1999

Scandinavian Journal of Infectious Diseases

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Pneumococcal endocarditis most often presents as an ulcerative endocarditis causing rapid destruction of the normal aortic valve, leading to aortic insufficiency and acute heart failure. Alcoholism is the most frequent underlying medical condition. This case illustrates that pneumococcal endocarditis can reoccur and is able to attack healthy, as well as previously damaged, heart valves. It also illustrates that vaccination of certain groups should be considered. The importance of repeated heart stethoscopy in patients with pneumococcaemia is emphasized.

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Pneumococcal endocarditis

Cited by 17 publications

References 66 publications

Infective Endocarditis and Other Intravascular Infections

Infective Endocarditis and Other Intravascular Infections

Pneumococcal Endocarditis in Adult Patients. A Report of Five Cases and Review of the Literature

Recurrent Endocarditis Caused by Streptococcus pneumoniae

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