PMx: software package for demographic and genetic analysis and management of pedigreed populations

Lacy, Robert C.; Ballou, Jonathan D.; Pollak, John P.

doi:10.1111/j.2041-210x.2011.00148.x

Cited by 102 publications

(121 citation statements)

References 12 publications

(13 reference statements)

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“…Pedigrees were maintained in an Access (Microsoft Corp.) database program developed by one of us (RCL) for the maintenance of records on research animal colonies, and genetic calculations on the pedigrees were performed with the pmx software (Lacy et al . ). The Institutional Animal Care and Use Committee of the Chicago Zoological Society approved all trapping, housing and husbandry protocols.…”

Section: Methodsmentioning

confidence: 97%

The impacts of inbreeding, drift and selection on genetic diversity in captive breeding populations

et al. 2014

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The goal of captive breeding programmes is often to maintain genetic diversity until re-introductions can occur. However, due in part to changes that occur in captive populations, approximately one-third of re-introductions fail. We evaluated genetic changes in captive populations using microsatellites and mtDNA. We analysed six populations of white-footed mice that were propagated for 20 generations using two replicates of three protocols: random mating (RAN), minimizing mean kinship (MK) and selection for docility (DOC). We found that MK resulted in the slowest loss of microsatellite genetic diversity compared to RAN and DOC. However, the loss of mtDNA haplotypes was not consistent among replicate lines. We compared our empirical data to simulated data and found no evidence of selection. Our results suggest that although the effects of drift may not be fully mitigated, MK reduces the loss of alleles due to inbreeding more effectively than random mating or docility selection. Therefore, MK should be preferred for captive breeding. Furthermore, our simulations show that incorporating microsatellite data into the MK framework reduced the magnitude of drift, which may have applications in long-term or extremely genetically depauperate captive populations.

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Section: Methodsmentioning

confidence: 97%

The impacts of inbreeding, drift and selection on genetic diversity in captive breeding populations

et al. 2014

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“…We used PMx 18 to evaluate number of generations in captivity (G) for each animal, calculated as the average G of an individual’s parents +1, where population founders are assigned G = 0. Note that G values are not necessarily whole numbers.…”

Section: Methodsmentioning

confidence: 99%

Increasing generations in captivity is associated with increased vulnerability of Tasmanian devils to vehicle strike following release to the wild

Grueber

Reid-Wainscoat

Fox³

et al. 2017

Sci Rep

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Captive breeding of threatened species, for release to the wild, is critical for conservation. This strategy, however, risks producing captive-raised animals with traits poorly suited to the wild. We describe the first study to characterise accumulated consequences of long-term captive breeding on behaviour, by following the release of Tasmanian devils to the wild. We test the impact of prolonged captive breeding on the probability that captive-raised animals are fatally struck by vehicles. Multiple generations of captive breeding increased the probability that individuals were fatally struck, a pattern that could not be explained by other confounding factors (e.g. age or release site). Our results imply that long-term captive breeding programs may produce animals that are naïve to the risks of the post-release environment. Our analyses have already induced changes in management policy of this endangered species, and serve as model of productive synergy between ecological monitoring and conservation strategy.

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“…Data from SPARKS are exported to the studbook analysis software PMx (Lacy et al 2012) for calculation and analysis of demographic, kinship, and inbreeding measures. Results presented in this paper are based on studbook data updated to mid 2011, complemented by qualitative observations of the captive animals.…”

Section: Studbook Management and Analysismentioning

confidence: 99%

The European Captive Population of Crowned Sifaka: 25 Years of Management

Roullet

2014

Primate Conservation

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PMx: software package for demographic and genetic analysis and management of pedigreed populations

Cited by 102 publications

References 12 publications

The impacts of inbreeding, drift and selection on genetic diversity in captive breeding populations

The impacts of inbreeding, drift and selection on genetic diversity in captive breeding populations

Increasing generations in captivity is associated with increased vulnerability of Tasmanian devils to vehicle strike following release to the wild

The European Captive Population of Crowned Sifaka: 25 Years of Management

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