PMMA-based ophthalmic contact lens for vision correction of strabismus

Asgharzadeh, Amir; Leland, Nordin; Tjossem, Paul J. H.; Abràmoff, Michael D.; Toor, Fatima

doi:10.1117/12.2237994

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…In the recent literature, PMMA has typically been utilized as a reference material for investigating various effects of CLs on the eye [64,65,66,67]. These works are some of many with a particular focus on the effect of the PMMA lens on eye conditions, such as astigmatism [64], strabismus [68], and blepharoptosis [65]. Aliό et al fitted patients who had received post-corneal refractive surgery with a variety of lens types, with RGP lenses showing the best results [64].…”

Section: Contact Lens Materialsmentioning

confidence: 99%

Contact Lens Materials: A Materials Science Perspective

2019

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More is demanded from ophthalmic treatments using contact lenses, which are currently used by over 125 million people around the world. Improving the material of contact lenses (CLs) is a now rapidly evolving discipline. These materials are developing alongside the advances made in related biomaterials for applications such as drug delivery. Contact lens materials are typically based on polymer- or silicone-hydrogel, with additional manufacturing technologies employed to produce the final lens. These processes are simply not enough to meet the increasing demands from CLs and the ever-increasing number of contact lens (CL) users. This review provides an advanced perspective on contact lens materials, with an emphasis on materials science employed in developing new CLs. The future trends for CL materials are to graft, incapsulate, or modify the classic CL material structure to provide new or improved functionality. In this paper, we discuss some of the fundamental material properties, present an outlook from related emerging biomaterials, and provide viewpoints of precision manufacturing in CL development.

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Section: Contact Lens Materialsmentioning

confidence: 99%

Contact Lens Materials: A Materials Science Perspective

2019

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“…Additions of natural gel material such as aloe Vera rich in hydration to PMMA contact lenses result in increasing the microstructure homogeneity making it smoother than pure PMMA due to the effect of gel filling the Nanopore structure as shown in figures (4,5)which present the SEM images of PMMA contact lenses with 0.1 aloe Vera, high homogeneity with no pore -structure obtained .figures (6,7) showed the SEM images of PMMA with 0.2% aloe Vera gel, an increasing in aloe gel lead to increase inhomogeneity and present uniform structure with high scale porosity due to an increasing OH content in PMMA chain structure, figures (8,9) showed the SEM images of PMMA with 0.3 % aloe Vera gel, small cracks began appears in structure as aloe Vera percentage increased due to the increase in amount on O-H bond which produces PMMA chains saturated with OH. adding more amount of aloe Vera has to make bad effect on PMMA structure and microsegregation appears in the structure as in figures (10,11) of 0.4% aloe Vera then high structure separation occurs at 0.5% aloe Vera as mentioned in figures (12,13). Fig.…”

Section: Microstructure Observation (Scanning Electron Microscopy (Sem))mentioning

confidence: 87%

“…PMMA has frequently been used as standard reference material in studies looking at the eye's response to various CLs [7][8][9] [10]. Astigmatism [7] strabismus [11], and Blepharoptosis [8]. are just a few of the eye conditions that have been shown to improve with the PMMA lens in previous studies.…”

Section: Introductionmentioning

confidence: 99%

Enhanced the Structure of Ophthalmic Implants (Rigid Contact Lenses) by Aloe Vera Addition

Alani

Alhasani

Hassani

2022

KEM

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Contact lenses are being used by more than 125 million people around the world for ophthalmic treatments. There has been a recent surge in interest in researching and developing new materials for contact lenses (CLs). With the advancement of associated biomaterials, such as drug delivery, these materials will continue to grow in importance in the future. If you're looking to buy contact lenses, you'll most likely find them made out of polymer or silicone hydrogel. To meet the ever-increasing needs for contact lenses and the ever-increasing number of contact lens users, this work aims to study the effect of adding aloe Vera gel to contact lenses, antibacterial behavior, surface texture, and wettability. Results show the addition of aloe Vera natural materials to rigid PMMA contact lenses aid to promote the performance of contact lenses by changing the internal structure of PMMA, especially when using (0.1%, 0.2%, and 0.3%) of aloe Vera due to the increasing in OH content as well as the increasing in the uniformity of microstructure. addition of (0.4% and 0.5 %) of aloe Vera make a reverse effect on the structure due to the saturation of PMMA chain with OH leading to destroying the connections between bonds, therefore, weakening PMMA lenses also using aloe Vera gel act to soften the lenses by increasing the OH content in PMMA structure lead to improving the lens wettability at about (0.2-0.3) % after these percentage large drop in whole properties will occur. Keywords: Rigid contact lens, PMMA, natural materials, Aloe Vera, OH content.

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