Pleomorphic adenoma of the upper lip: a case report and review of literature

Abstract

<p>Pleomorphic Adenoma is a benign epithelial tumor arising from the salivary gland. It is a benign mixed tumor composed of epithelial and myoepithelial cells arranged with various morphological patterns, demarcated from surrounding tissues by fibrous capsule. In this article, we report an unusual case of 30 year, male with a single, nodular swelling evident in the upper lip which was discovered during a routine dental procedure. Fine Needle Aspiration Cytology (FNAC) was planned for the patient, where a of cytological diagnosis of Pleomorphic Adenoma was rendered, which was confirmed by biopsy. Hence, this highlights, FNAC makes up an important diagnosing tool as the first line of investigation to distinguish between benign and malignant salivary gland neoplasms.</p>

Lip pleomorphic adenomas: case series and literature review

“…We conducted a search of the literature on lip PAs (in Japan and worldwide) and found 35 cases described in 31 reports since 2000 (Table 2) (10,11,14-17,19-22,26-39,41). Of the 35 past cases of lip PA, 30 (85.7%) were in the upper lip (10,11,13,15,17,(19)(20)(21)(23)(24)(25)(26)(28)(29)(30)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41) and only five (14.3%) were in the lower lip (14,16,22,27,31). The male-tofemale ratio of the lip PAs was 4:3 (a nonsignificant difference), and the age range was from 10 to 72 years (Table 2).…”

Pleomorphic Adenoma of the upper lip: A diagnostic quandary due to coinciding traumatic history – A rare case report

“…Microphotograph of pleomorphic adenoma in magnifications of 20x and 40x showing seeds and cords of benign epithelial cells, myoepithelial cells and occasional cystically dilated spaces with focal hyalinization were seen. (Figure 2A and Figure 2B) Discussions PA is rarely found in the minor salivary glands, but a few cases have been found that most commonly involve the palate followed by upper lip and buccal mucosa [4] . Literature suggests that the average age of presentation is between 40 -60 years with a slight female predilection which was consistent with our case study [5] .…”

A rare case report of pleomorphic adenoma of the upper lip: An unusual clinical presentation

“…There is a propensity for the benign tumor to occur in the upper lip may be due to differences in embryonic development between upper and lower lips. [ 7 ] whereas malignant lesions to predominate in the lower lip. [ 8 9 ] We have reviewed the few clinical differential diagnosis of a swelling of the upper lip, as likelihood like in Canalicular adenoma, pleomorphic adenoma, lipoma, fibroma, adenoid cystic carcinoma, mucoepidermoid carcinoma, and nasolabial cyst.…”