Pleomorphic Adenoma of the Trachea Mimicking Bronchial Asthma: Report of a Case

Abstract

Benign tracheal tumors are rare and difficult to diagnose. A delay in diagnosis is common because the symptoms mimic those of bronchial asthma. We report the case of a 42-year-old woman who was treated for asthma for 2 years before a diagnosis of pleomorphic adenoma of the trachea was made. To our knowledge, only 33 patients with pleomorphic adenoma of the trachea have been reported. We treated our patient by performing circumferential segmental tracheal resection and end-to-end anastomosis. A dynamic Y-stent was implanted for tracheal stenosis soon after the operation and it was removed 2 years later. The patient is now asymptomatic and no recurrence has been detected in the 5 years since diagnosis.

Pleomorphic Adenoma with an Endobronchial Resection

“…3B, C) (4,5). Including the present case and Japanese language case reports, up to 50 cases have presently been reported (3)(4)(5)(6)(7)(8)(9)(10)(11).…”

“…A surgical resection is not used when the patient is in poor condition (9), refuses surgery (10) or is of advanced age (11). The longest follow-up period is 5 years (11) (1,(3)(4)(5)(6)(7)(8). Furthermore, there are two reports of malignant pleomorphic adenomas (7,8).…”

“…Furthermore, there are two reports of malignant pleomorphic adenomas (7,8). Many of the reports (3)(4)(5)(6) regarding pleomorphic adenoma stated that surgical resection is the best therapeutic choice for this disease based on those previous reports (7,8). However, one of the studies addressing malignant pleomorphic adenoma (8) …”

Bronchial Pleomorphic Adenoma Coexisting with Lung Cancer

“…4) Only 35 cases of tracheobronchial pleomorphic adenoma have been reported in the literature. [5][6][7] There is no clear gender or age predominance: the ages ranging between 8 and 74 years. 1,3,6,8) Pleomorphic adenomas are benign neoplasms with mixed epithelial and mesenchymal components.…”

Pleomorphic Adenoma of the Subglottis Mistreated as Chronic Obstructive Pulmonary Disease, Report of a Case

“…Approximately many cases may be misdiagnosed, leading to aggressive treatment. Kokturk N, et al 8) and Aribas OK, et al 9) respectively reported that the patient with pleomorphic adenoma of the trachea was misdiagnosed as asthma. Because of the rarity and histological variants of the tumor, surgical resection seems to be the reasonable choice.…”