Pleomorphic adenoma of nasal septum

Sen, Sumit; Basu, Nandita

doi:10.1007/bf02907682

Cited by 4 publications

(5 citation statements)

References 8 publications

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“…Patients can have painless, unilateral nasal blockage, epistaxis, sinusitis, or mass within the nasal cavity. Other nasal symptoms such as nasal swelling, anosmia, epiphora, and mucopurulent rhinorrhea may also be present [ 2 , 3 , 6 ]. Rhinoscopy or rigid nasoendoscopy will show a unilateral, smooth surface, pale grayish whitish mass [ 4 , 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…Pleomorphic adenoma is a slow-growing tumor, but it has a high rate of recurrence of approximately 50% for parotid gland tumors and low recurrence rate of 10% for intranasal tumors [ 6 ]. Histopathology examination shows manifestation of both epithelial and mesenchymal components.…”

Section: Discussionmentioning

confidence: 99%

“…This is important to avoid disease recurrence [ 1 - 3 ]. Options for removal of tumor vary depending on the size and location of the tumor, such as endoscopic resection, intra-nasal excision lateral rhinotomy, and midfacial degloving [ 1 , 2 , 6 , 7 ]. Nasal endoscopic resection was performed in our patient as the mass was limited to the anterior aspect of the nasal cavity.…”

Section: Discussionmentioning

confidence: 99%

“…Pleomorphic adenoma of the minor salivary glands can be found at locations where the minor salivary glands exist, such as the neck, ear, mediastinum, external nose, cheek, and nasal cavity [ 2 , 4 , 6 , 7 ]. Lesion detected in the nasal cavity is rare, and for most of the cases, the tumor originates from the mucosa of the nasal septum even though the seromucosal glands are mainly at the lateral nasal wall [ 2 , 3 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

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Pleomorphic Adenoma of the Nasal Septum: A Case Report

Salahuddin¹,

Sairin²

2022

Cureus

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Pleomorphic adenoma is the most common benign tumor of major and minor salivary glands. It rarely originates from the nasal cavity. It is important to identify the symptoms and characteristics of the disease so that early diagnosis can be made and appropriate treatment can be offered as it has a risk of malignant transformation. We are reporting a case of a 22-year-old female with a long duration of unilateral nasal obstruction. Rigid nasoendoscopy showed a mass at the left nasal septum. Preoperative imaging was performed followed by endoscopic resection of the mass. The pathological diagnosis was pleomorphic adenoma. Post-operatively, appropriate examination with nasoendoscopy and long-term follow-up is essential to avoid local recurrence.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Pleomorphic Adenoma of the Nasal Septum: A Case Report

Salahuddin¹,

Sairin²

2022

Cureus

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“…The etiopathogenesis of PAs remains unknown. The prevailing theories regarding their origin include vomeronasal organ residues [ 6 ] and mature salivary gland tissue [ 7 ]. Histologically, sinonasal and nasopharyngeal PAs are predominantly epithelial, with less mesenchymal stroma, and they are devoid of capsules, in comparison with mixed tumors of the major salivary glands [ 8 ].…”

Section: Introductionmentioning

confidence: 99%

Diagnostic Challenges of Sinonasal Pleomorphic Adenoma

Konsulov,

Milkov,

Markov

et al. 2024

Cureus

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Pleomorphic adenomas (PAs) are benign tumors of the salivary glands. Rarely, they arise in the sinonasal cavity, presenting as well-defined, homogeneous soft tissue masses, causing expansive bony changes. The significance of PAs is the possibility of giving rise to malignant carcinoma - “carcinoma ex-pleomorphic adenoma” (CXPA).Here, we present the case of a 64-year-old female complaining of progressive unilateral congestion and external nose deformation, mostly along the left contour of the radix, with epiphora of the ipsilateral eye. Eventually, a tumor began protruding from the left naris. The computed tomography excluded osteolysis, while the surgical procedure discovered the inferior turbinate as the origin of the tumor. In addition, the ipsilateral maxillary sinus was found to have developed secondary sinusitis. After complete surgical excision, the histological result was sinonasal melanoma, but following no progression of the disease, a second pathologist with additional immunohistochemical markers (HMB-45 (human melanoma black 45) negative, Melan-A (melanoma antigen recognized by T-cells 1) negative, S100 (protein soluble in 100% ammonium sulfate at neutral pH) positive, panCK AE1/AE3 (pan cytokeratin antibodies AE1 and AE3) negative, p63 (tumor protein 63) negative, Ki-67 (marker of proliferation Kiel 67) 10%, CD68 (cluster of differentiation 68) negative, CK7 (cytokeratin 7) negative, and CDX2 (caudal-type homeobox 2) negative) placed the definitive diagnosis of PA.PA of the inferior turbinate is an extremely rare finding, with the clinical symptoms being unspecific. Sometimes, SOX-10 (SRY-box transcription factor 10) positivity can mislead to malignant melanoma, as in our case, which is why a broad panel of immunohistochemical markers is critical for the definitive diagnosis.

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Huge pleomorphic adenoma of nasal cavity

Ekhar

Mahore

2007

Indian J Otolaryngol Head Neck S

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Pleomorphic adenoma is a common benign tumour of the salivary gland that has elements of both epithelial and mesenchymal tissue. It is commonly seen in major salivary glands, parotid being the most common site followed by submandibular gland. However it can sometimes arise from minor salivary glands that are distributed throughout the upper aerodigestive tract and paranasal sinuses. We report a case of a 45 yrs. Old male patient, who presented with progressive nasal blockage and intermittent minor episodes of epistaxis from left nostril for 1 ½ years. Lateral Rhinotomy revealed a well encapsulated lesion attached to the nasal septum, which was excised completely. Histopathology revealed it to be Pleomorphic Adenoma without any features of malignancy. Lesion is a rare one hence reported.

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Pleomorphic adenoma of nasal septum

Cited by 4 publications

References 8 publications

Pleomorphic Adenoma of the Nasal Septum: A Case Report

Pleomorphic Adenoma of the Nasal Septum: A Case Report

Diagnostic Challenges of Sinonasal Pleomorphic Adenoma

Huge pleomorphic adenoma of nasal cavity

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