Platelet-rich plasma in aesthetics

Nanda, Soni; Chauhan, Kavish; Shetty, Vinma H.; Dashore, Shuken; Bhatia, Sumati

doi:10.4103/idoj.idoj_290_21

Cited by 10 publications

(6 citation statements)

References 54 publications

(64 reference statements)

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“…Since PRP has the potential to activate the synthesis of extracellular matrix elements including collagen [16][17][18], it has been used for dermatological disease and cosmetic problems including skin rejuvenation for about a decade [1,3,5,19,20]. An earlier study examined the use of PRP injections for face and neck rejuvenation in 23 patients and found clinical improvement (in terms of nasolabial folds, horizontal neck bands, skin microrelief for snap test, skin homogeneity and texture, skin tonicity, and periocular wrinkles) in addition to patient and physician satisfaction [19].…”

Section: Discussionmentioning

confidence: 99%

“…Facial skin rejuvenation aims to reverse aging process to restore younger cosmetic appearance, either with surgical or nonsurgical cosmetic procedures, latter being more demanded recently [1]. Among nonsurgical approaches, injection of platelet-rich plasma (PRP), a platelet concentrate obtained from autologous plasma, has recently gained popularity for facial skin rejuvenation, as well as for other dermatological conditions [1][2][3][4][5]. PRP contains a wide range of proteins/growth factors including platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and transforming growth factor beta (TGFβ); thus, has the potential to rejuvenate the skin through improvement of angiogenesis, tissue remodeling, stem cell stimulation, cellular proliferation/regeneration, and hyaluronic acid production [3].…”

Section: Introductionmentioning

confidence: 99%

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The Comparison of Platelet-Rich Plasma Versus Injectable Platelet Rich Fibrin in Facial Skin Rejuvenation

Atsü

Ekinci-Aslanoglu

Kantarci-Demirkiran

et al. 2023

Dermatologic Therapy

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Background/Objective. Platelet-rich plasma (PRP) has a widespread use in various indications including dermatological conditions. Injectable platelet-rich fibrin on the other hand is prepared without anticoagulants and seems to have a sustained action. This study aimed to compare PRP and PRF injection treatments for facial skin rejuvenation in terms of efficacy, patient satisfaction, and side effects. Patients and Methods. Patients who received facial intradermal injections of PRP or PRF for skin rejuvenation were included in this study. Patients received three injections one month apart and evaluated at follow-up visits for cosmetic results using a high-resolution UVA-light video camera and a surface evaluation software at three regions (frontal, nasolabial, and canthal) as well as for patient satisfaction and side effects. Results. A significant marginal superiority of PRF over PRP was only evident for some canthal cosmetic parameters (canthal smoothness and wrinkles); however, the two groups did not differ in terms of other cosmetic regional parameters. For canthal smoothness, the difference was significant at three months. The two groups did not differ in terms of side effects, pain, and patient satisfaction. Conclusion. This study obtained slightly better outcomes with PRF injections when compared to PRP for facial rejuvenation only at canthal region and only at three months, which disappeared later during the treatment. PRF may represent a viable alternative to PRP for that indication owing to its easier preparation, absence of anticoagulants, and possibly its sustained effect. Further large studies are warranted.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Comparison of Platelet-Rich Plasma Versus Injectable Platelet Rich Fibrin in Facial Skin Rejuvenation

Atsü

Ekinci-Aslanoglu

Kantarci-Demirkiran

et al. 2023

Dermatologic Therapy

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“…When PRP is injected in dermis, it causes a mild inflammatory reaction of skin, stimulating the healing process. As a result, collagen synthesis is triggered, and the skin may become tightened and strengthened 37 . Skin condition improvement is noticeable within 3 weeks.…”

Section: Classification Of Skin Boostersmentioning

confidence: 99%

Skin boosters: Definitions and varied classifications

Yi,

Winayanuwattikun,

Kim

et al. 2024

Skin Research and Technology

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BackgroundThe concept of “skin boosters” has evolved, marking a shift from traditional uses of hyaluronic acid (HA) fillers primarily for augmenting skin volume to a more diverse application aimed at improving dermal conditions. Restylane Vital and other HA fillers have been repurposed to combat skin aging and wrinkles by delivering HA directly to the dermis.ObjectivesThis review aims to define the term “skin booster” and to discuss the various components that constitute skin boosters. It seeks to provide a comprehensive overview of the different ingredients used in skin boosters, their roles, and their impact on enhancing dermal conditions.MethodsA comprehensive review was conducted, focusing on representative skin booster ingredients. The approach involved analyzing the different elements used in skin boosters and their specific roles in enhancing dermal improvement.ResultsThe findings indicate that skin boosters, encompassing a range of ingredients, are effective in improving the condition of the skin's dermis. The review identifies key ingredients in skin boosters and their specific benefits, including hydration, elasticity improvement, and wrinkle reduction.ConclusionsSkin boosters represent a significant development in dermatological treatments, offering diverse benefits beyond traditional HA fillers. This review provides valuable insights into the constituents of skin boosters and their effectiveness, aiding readers in making informed decisions about these treatments. The potential of skin boosters in dermatological practice is considerable, warranting further research and application.

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“…Although it is difficult to find freely available information on how EVs were isolated and characterised in these products, we can comment on dose. In the Zen [3] product developed by Exoskin Simple, 15 million EVs are combined in a 10 oz. skincare formulation.…”

Section: Commercial Landscapementioning

confidence: 99%

“…smoking, poor diet). Lastly, these autologous treatments are highly heterogeneous and present challenges in their scale up and standardisation, with therapeutic efficacy varying depending on the method of preparation and a limited understanding of the precise mechanism(s) of biological action [3]. As such, there is a need to develop novel regenerative strategies that can be applied in regenerative dermatology which offer improved reproducibility, scalability and efficacy when compared with current approaches.…”

Section: Introductionmentioning

confidence: 99%