Platelet enhancement by Carica papaya L. leaf fractions in cyclophosphamide induced thrombocytopenic rats is due to elevated expression of CD110 receptor on megakaryocytes

Carica papaya L. Leaves: Deciphering Its Antioxidant Bioactives, Biological Activities, Innovative Products, and Safety Aspects

“…Beside vitamins E, A, and C, they have vitamin B-17 whose concentrated form is used to cure cancer patients in conventional chemotherapy treatment. Phytochemicals of papaya leaves have been reported to prevent bone marrow depletion and platelet destruction [ 2 ]. Juice of papaya leaf is quite helpful to elevate platelet count and red blood and white blood cells to normalize blood clotting and to repair the liver [ 18 ].…”

“…C. papaya L. belongs to the family Caricaceae and is commonly known as papaya, pawpaw, and kates. It is a perennial horticultural shrub originated from Mesoamerican Centre, Central America, and southern Mexico [ 2 – 4 ] and is mainly cultivated in the tropical and subtropical regions of Brazil, Australia, Malaysia, China, India, Thailand, Myanmar, Philippines, and other adjoining [ 5 ]. Papaya is not only cultivated for the ripe sweet fruit, even other parts of the plant such as seeds, leaves, roots, flowers, barks, and latex have been traditionally used worldwide for the preparation of various medicinal formulations [ 6 , 7 ].…”

CONTRIBUCIÓN POTENCIAL DE LAS SEMILLAS DE Carica papaya Linn Y SU ACEITE EN LA SALUD

“…RESUMEN: El propósito de la presente investigación fue analizar las potencialidades de las semillas de Carica papaya Linn y aceite para su aprovechamiento como factor determinante en la salud. Por lo cual, se realizó una revisión bibliográfica exhaustiva con enfoque cualitativo de tipo descriptivo, documentados en estudios científicos de autores como Gudimella et al, (2022); Gnanamangai et al, (2022); Rao et al, (2022); Pereira et al, (2021); Nandini et al, (2021); Agada et al, (2020); Hafid et al, (2020); Ávila et al, (2020), Morais et al, (2017); Sharma et al, (2016); entre otros. Las semillas presentaron alto contenido de proteínas, carbohidratos, lípidos, fibra, minerales, fitoquímicos que incluyen antioxidantes los cuales brindan un alto valor nutricional beneficiando la salud de poblaciones desnutridas.…”

“…ABSTRACT: The purpose of this research was to analyze the potential of Carica papaya Linn seeds and oil for their use as a determining factor in health. Therefore, an exhaustive bibliographic review was carried out with a descriptive qualitative approach, documented in scientific studies by authors such as Gudimella et al, (2022); Gnanamangai et al, (2022); Rao et al, (2022); Pereira et al, (2021); Nandini et al, (2021); Agada et al, (2020); Hafid et al, (2020); Ávila et al, (2020), Morais et al, (2017); Sharma et al, (2016); among others. The seeds presented a high content of proteins, carbohydrates, lipids, fiber, minerals, phytochemicals that include antioxidants, which provide a high nutritional value, benefiting the health of undernourished populations.…”

“…Las hojas de Carica papaya Linn son reconocidas en etnomedicina por su actividad potenciadora de plaquetas, el extracto obtenido de su cocción es utilizado en países como Malasia y parte de la India para incrementar el recuento de las mismas, a pesar de que estudios clínicos y preclínicos han demostrado que efectivamente el extracto de las hojas tiene estas potencialidades los mecanismos subyacentes aún no están claros (Nandini et al, 2021).…”