Plasmonic Biosensors: Review

Hamza, Mohga E.; Othman, Muhammad A.; Swillam, Mohamed A.

doi:10.3390/biology11050621

Cited by 37 publications

(33 citation statements)

References 179 publications

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“…sensor, made of gold (Au), which is used to characterize biomolecular interactions [23]. SPR systems are based on an optical phenomena pioneered by Wood in the 1980s, which is a gold standard method.…”

Section: Surface Plasmon Resonance (Spr)mentioning

confidence: 99%

“…Plasmonic biosensors have shown the potential to detect pollutants directly and reliably in the environment. The most common analytes detected by biosensors for environmental monitoring include heavy metals in water, pesticides, and potentially toxic and dangerous chemicals such as explosives [19,23,[47][48][49]. Conventional sensing substrates have been improved with plasmonic materials for enhanced performance.…”

Section: Biosensing For Environmental Monitoringmentioning

confidence: 99%

See 1 more Smart Citation

Application of Plasmonic Nanostructures in Molecular Diagnostics and Biosensor Technology: Challenges and Current Developments

Nyembe¹,

Mkhohlakali²,

May³

et al. 2023

Plasmonic Nanostructures - Basic Concepts, Optimization and Applications

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The recent global pandemic caused by Covid-19 enforced the urgent need for accessible, reliable, and accurate point-of-care rapid diagnostics based on plasmonic nanostructures. This is because fast and reliable testing was the key driver in curbing the spread of Covid-19. The traditional methods of diagnostics and biosensors often require expensive infrastructure and highly qualified and trained personnel, which limits their accessibility. These limitations perpetuated the impact of Covid-19 in most countries because of the lack of easily accessible point-of-care rapid diagnostic kits. This review revealed that portable and reliable point-of-care diagnostic kits are very crucial in reaching large populations, especially in underdeveloped and developing countries. This gives perspective to novel point-of-care applications. Furthermore, water quality is a very crucial part of food safety, especially in developing countries faced with water contamination. In this chapter, we explored the various challenges and recent developments in the use of plasmonic nanostructures for application in molecular diagnostics and biosensing for the detection of infectious diseases and common environmental pathogens.

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Section: Surface Plasmon Resonance (Spr)mentioning

confidence: 99%

Section: Biosensing For Environmental Monitoringmentioning

confidence: 99%

Application of Plasmonic Nanostructures in Molecular Diagnostics and Biosensor Technology: Challenges and Current Developments

Nyembe¹,

Mkhohlakali²,

May³

et al. 2023

Plasmonic Nanostructures - Basic Concepts, Optimization and Applications

View full text Add to dashboard Cite

show abstract

“…Sensors for detecting chemical and biological substances are one of the most well-studied uses of plasmonic materials [ 140 , 141 ]. One method involves coating a plasmonic nanomaterial with a chemical that binds to a target molecule, such as a bacterial toxin.…”

Section: Bg Structures Based On the Plasmonic Platformmentioning

confidence: 99%

Advances in Waveguide Bragg Grating Structures, Platforms, and Applications: An Up-to-Date Appraisal

2022

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A Bragg grating (BG) is a one-dimensional optical device that may reflect a specific wavelength of light while transmitting all others. It is created by the periodic fluctuation of the refractive index in the waveguide (WG). The reflectivity of a BG is specified by the index modulation profile. A Bragg grating is a flexible optical filter that has found broad use in several scientific and industrial domains due to its straightforward construction and distinctive filtering capacity. WG BGs are also widely utilized in sensing applications due to their easy integration and high sensitivity. Sensors that utilize optical signals for sensing have several benefits over conventional sensors that use electric signals to achieve detection, including being lighter, having a strong ability to resist electromagnetic interference, consuming less power, operating over a wider frequency range, performing consistently, operating at a high speed, and experiencing less loss and crosstalk. WG BGs are simple to include in chips and are compatible with complementary metal-oxide-semiconductor (CMOS) manufacturing processes. In this review, WG BG structures based on three major optical platforms including semiconductors, polymers, and plasmonics are discussed for filtering and sensing applications. Based on the desired application and available fabrication facilities, the optical platform is selected, which mainly regulates the device performance and footprint.

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“…A different approach involves the so-called “localized surface plasmon resonance” (LSPR), a term that is used to describe the electron density wave that travels over the metal surface. Plasmonic biosensors are a class of devices that use sensitive noble metal nanoparticles (NPs) integrated into a biosensing assembly for applications in environmental pollution analysis, illness diagnosis, and human health monitoring (viral detection) [ 18 , 19 , 20 , 21 ].…”

Section: Mems: Classification and Employmentmentioning

confidence: 99%

Sensing Devices for Detecting and Processing Acoustic Signals in Healthcare

et al. 2022

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Acoustic signals are important markers to monitor physiological and pathological conditions, e.g., heart and respiratory sounds. The employment of traditional devices, such as stethoscopes, has been progressively superseded by new miniaturized devices, usually identified as microelectromechanical systems (MEMS). These tools are able to better detect the vibrational content of acoustic signals in order to provide a more reliable description of their features (e.g., amplitude, frequency bandwidth). Starting from the description of the structure and working principles of MEMS, we provide a review of their emerging applications in the healthcare field, discussing the advantages and limitations of each framework. Finally, we deliver a discussion on the lessons learned from the literature, and the open questions and challenges in the field that the scientific community must address in the near future.

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Plasmonic Biosensors: Review

Cited by 37 publications

References 179 publications

Application of Plasmonic Nanostructures in Molecular Diagnostics and Biosensor Technology: Challenges and Current Developments

Application of Plasmonic Nanostructures in Molecular Diagnostics and Biosensor Technology: Challenges and Current Developments

Advances in Waveguide Bragg Grating Structures, Platforms, and Applications: An Up-to-Date Appraisal

Sensing Devices for Detecting and Processing Acoustic Signals in Healthcare

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