2008
DOI: 10.1128/aac.01180-07
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Plasmid-Mediated Carbapenem-Hydrolyzing β-Lactamase KPC-2 in Klebsiella pneumoniae Isolate from Greece

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Cited by 92 publications
(74 citation statements)
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“…In previous studies, all bla KPC -encoding plasmids found in Hangzhou carried only the bla KPC-2 gene (Cai et al, 2008a, b;Wei et al, 2007;Zhang et al, 2007Zhang et al, , 2008. Many bla KPCencoding plasmids also encode bla TEM-1 (Cuzon et al, 2008;Dortet et al, 2008;Leavitt et al, 2007;Miriagou et al, 2003;Naas et al, 2005Naas et al, , 2008, some encode bla SHV (Robicsek et al, 2006;Yigit et al, 2003), bla CTX-M (Cuzon et al, 2008;Dortet et al, 2008;Leavitt et al, Fig. 2.…”
Section: Pcr and Dna Sequence Analysismentioning
confidence: 99%
See 1 more Smart Citation
“…In previous studies, all bla KPC -encoding plasmids found in Hangzhou carried only the bla KPC-2 gene (Cai et al, 2008a, b;Wei et al, 2007;Zhang et al, 2007Zhang et al, , 2008. Many bla KPCencoding plasmids also encode bla TEM-1 (Cuzon et al, 2008;Dortet et al, 2008;Leavitt et al, 2007;Miriagou et al, 2003;Naas et al, 2005Naas et al, , 2008, some encode bla SHV (Robicsek et al, 2006;Yigit et al, 2003), bla CTX-M (Cuzon et al, 2008;Dortet et al, 2008;Leavitt et al, Fig. 2.…”
Section: Pcr and Dna Sequence Analysismentioning
confidence: 99%
“…P, K. pneumoniae K1 isolated from the 2nd Affiliated Hospital of Zhejiang University (producing KPC-2, TEM-1, SHV-11 and CTX-M-14); t, E. coli transconjugant; M, strain producing TEM-28 (pI 6.1), SHV-7 (pI 7.6) and ACT-1 (pI 9.0). Monteiro et al, 2009;Naas et al, 2008;Tsakris et al, 2008;Yigit et al, 2003) and some encoded qnr (Chmelnitsky et al, 2008;Endimiani et al, 2008;Mendes et al, 2008). Unlike these, most bla KPC -encoding plasmids in this study were associated with four drug-resistance genes.…”
Section: Pcr and Dna Sequence Analysismentioning
confidence: 99%
“…PCR and sequence analysis with primers for detection of Ambler class D and class B, and class A b-lactamaseencoding genes (Cuzon et al, 2008b), identified an OXA-48-type b-lactamase together with the bla CTX-M-15 genes. Sequencing identified a variant of the class D carbapenemase OXA-48 (differing by 4 amino acid substitutions) that corresponds to the carbapenemase OXA-181.…”
Section: Case Reportmentioning
confidence: 99%
“…Some isolates are susceptible to amikacin and gentamicin and most are susceptible to colistin and tigecycline (30,(33)(34)(35).…”
Section: Discussionmentioning
confidence: 99%