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Cited by 24 publications
(17 citation statements)
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“…8 These findings are consistent with those of our group's prior studies, which have shown that this rebound can be reduced in animals 11 and in humans 12 by using immunosuppressive agents that inhibit antibody synthesis. Our results are nearly identical to those reported previously that the rebound in antibody levels that follows pemphigus antibody depletion by plasmapheresis was suppressed by the concurrent administration of an immunosuppressive agent.…”
Section: Commentsupporting
confidence: 89%
See 1 more Smart Citation
“…8 These findings are consistent with those of our group's prior studies, which have shown that this rebound can be reduced in animals 11 and in humans 12 by using immunosuppressive agents that inhibit antibody synthesis. Our results are nearly identical to those reported previously that the rebound in antibody levels that follows pemphigus antibody depletion by plasmapheresis was suppressed by the concurrent administration of an immunosuppressive agent.…”
Section: Commentsupporting
confidence: 89%
“…The rebound can be suppressed in animals by the coadministration of a cytotoxic drug such as cyclophosphamide. 11 This strategy has been applied to improve the effectiveness of the plasmapheresis treatment of pemphigus, 12 a procedure that also rapidly lowers serum levels of pathogenic antibodies. We have speculated that the coadministration of an immunosuppressive agent will similarly improve the effectiveness of IVIg in pemphigus and other autoantibody-mediated blistering diseases.…”
mentioning
confidence: 99%
“…These observations strongly indicate the pathogenic relevance of Dsg1/3-reactive IgG autoantibodies in pemphigus and provide a rationale for utilizing therapeutic approaches aimed at removing circulating autoantibodies in PV and PF. Several groups successfully performed plasmapheresis in cases of severe or recalcitrant pemphigus [9,10,11]. Since plasmapheresis nonspecifically removes plasma proteins including clotting factors, hormones and albumin, the method of immunoadsorption (IA) was introduced as a more specific approach eliminating immunoglobulins and circulating immune complexes [12].…”
Section: Introductionmentioning
confidence: 99%
“…Plasmapheresis (Cotterill et al, 1978;Blaszczyk et al, 1981;Swanson and Dahl, 1981;Roujeau et al, 1982;Bystryn, 1988;Roujeau, 1993;Turner et al, 2000) sometimes with cyclosporin (Ruocco, 1988) or cyclophosphamide (Kiel synchronization protocol) and extracorporeal photophoresis (Edelson, 1984) have also been reported to be of benefit.…”
Section: Plasmapheresismentioning
confidence: 99%