“…IVIg, 2 g/kg/month, was given on 4–5 consecutive days as a slow, approximately 4‐hour infusion, hereinafter referred to as “IVIg cycle.” Prior to each infusion, the patients were premedicated with 50 mg diphenhydramine and 500 mg acetaminophen. To prevent a rebound effect from compensatory overproduction of pemphigus antibodies by the autoantibody‐producing cells stimulated via a negative feedback due to rapid clearance of pathogenic IgGs, IVIg was combined with the ICD mycophenolate mofetil 2 g/day, azathioprine 200 mg/day, or cyclophosphamide 150 mg/day, chosen in the above order depending on the patient's insurance allowance as well as counter‐indications and adverse reactions (Fig. a).…”