Plasmablastic lymphoma: a rare and exuberant cutaneous emergence in an immunocompetent patient

Tavares, Mara Diane Lisboa; Magalhães, Taíssa Canedo de; Moraes, Fernando Manuel Belles de; Piñeiro-Maceira, Juãn; Ramos‐e‐Silva, Márcia

doi:10.1111/ijd.12705

Cited by 2 publications

(3 citation statements)

References 14 publications

(19 reference statements)

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“…Only one other report has described skin findings secondary to relapse from a different primary source (the oral cavity), as was the case in our patient. 5 The most common clinical presentation involves erythematous to violaceous papules or nodules, occasionally associated with ulceration and necrosis. From the published studies of cutaneous PBL, 19 (64%) were male and 10 (36%) were female, with a median age of 52 years.…”

Section: Discussionmentioning

confidence: 99%

Relapse of Plasmablastic Lymphoma With Cutaneous Involvement in an Immunocompetent Male

et al. 2020

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Plasmablastic lymphoma (PBL) is a rare type of non-Hodgkin lymphoma frequently found in the context of immunosuppression and infection with human immunodeficiency virus (HIV) and/or Epstein-Barr virus (EBV). A 33-year-old immunocompetent male presented with recurrent episodes of epistaxis and a growing intranasal mass. Excisional biopsy of the mass revealed an immunohistochemical profile diagnostic of PBL. Upon completion of chemoradiation, he underwent a transnasal endoscopic mucosal flap tissue rearrangement to restore patency for both functional and surveillance purposes. There was no endoscopic evidence of residual or recurrent disease. However, 8 months later, he was found to have a relapse involving the skin. The nasal cavity is one of the most common sites affected by PBL. Involvement of the nasal cavity may present with symptoms of persistent epistaxis accompanied by an enlarging mass. A plasmablastic immunophenotype in combination with HIV or EBV positivity can aid diagnosis.

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Section: Discussionmentioning

confidence: 99%

Relapse of Plasmablastic Lymphoma With Cutaneous Involvement in an Immunocompetent Male

et al. 2020

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“…5 Its diagnosis implies the investigation of subjacent immunosuppression, particularly HIV-induced. However, it can also be observed in patients in immunosenescence state when the term plasmablastic lymphoma of the elderly (PBL-E) is used.…”

Section: Discussionmentioning

confidence: 99%

“…3 Primary cutaneous plasmablastic lymphomas are extremely rare with only 12 cases reported by 2014. 4,5 We present a clinical case of highly aggressive primary cutaneous plasmablastic lymphoma revealing clinically unsuspected HIV infection.…”

Section: Introductionmentioning

confidence: 99%

Primary cutaneous plasmablastic lymphoma revealing clinically unsuspected HIV infection

Marques

Abbade

Guiotoku³

et al. 2016

An. Bras. Dermatol.

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Plasmablastic lymphoma: a rare and exuberant cutaneous emergence in an immunocompetent patient

Cited by 2 publications

References 14 publications

Relapse of Plasmablastic Lymphoma With Cutaneous Involvement in an Immunocompetent Male

Relapse of Plasmablastic Lymphoma With Cutaneous Involvement in an Immunocompetent Male

Primary cutaneous plasmablastic lymphoma revealing clinically unsuspected HIV infection

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