Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers

Sales, Márcia Cristina; Oliveira, Larissa Praça de; Cabral, Natália Louise de Araújo; Sousa, Sara Estéfani Soares de; Almeida, Maria das Graças; Lemos, Telma Maria Araújo Moura; Lyra, Clélia de Oliveira; Lima, Kênio Costa de; Sena-Evangelista, Karine Cavalcanti Maurício; Pedrosa, Lucía

doi:10.1016/j.jtemb.2018.04.026

Cited by 21 publications

(22 citation statements)

References 34 publications

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“…Data concerning sex, age, type of institution, date of admission to the NH, reason(s) for institutionalization, and institutionalization time were used to analyze the socio-demographic profiles of the participants. Institutionalization time was adjusted for age, considering that the age at which an individual was institutionalized would influence his/her health, according to the following formula: 26 , 27

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Section: Methodsmentioning

confidence: 99%

Frequency of metabolic syndrome and associated factors in institutionalized elderly individuals

Sales

Oliveira

Liberalino³

et al. 2018

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IntroductionPopulation aging generally accompanies an increase in chronic noncommunicable diseases, such as metabolic syndrome (MS). Nursing homes have provided a solution for the decreased ability of elderly individuals for self-care and familial difficulties in meeting the health care needs of elderly individuals.PurposeThe aim of the present study was to determine the frequency of MS and its associated factors in elderly individuals living in nursing homes.Patients and methodsThis cross-sectional study was conducted with 202 institutionalized elderly individuals. MS was diagnosed according to the National Cholesterol Education Program – Adult Treatment Panel III criteria. Sociodemographic, clinical, and lifestyle factors were assessed to verify their association with MS by logistic regression.ResultsThe MS frequency was 29.2%. The most frequent MS components were low high-density lipoprotein cholesterol level (63.9%) and abdominal obesity (42.7%). Factors associated with MS were female sex (prevalence ratio [PR]=2.16; 95% CI, 1.04–4.49), age-adjusted institutionalization time >50% (PR=2.38, 95% CI, 1.46–3.88), and high concentrations of interleukin-6 (PR=2.01; 95% CI, 1.21–3.32) and tumor necrosis factor-α (PR=1.70; 95% CI, 1.05–2.77). Moreover, it was verified that the likelihood of having MS was 1.85-fold higher (95% CI, 1.11–3.10) in the group with a diet characterized by very high energy, very low fat, and high dietary fiber.ConclusionThe occurrence of MS in institutionalized elderly individuals was higher in females, and individuals with longer age-adjusted institutionalization time, higher concentrations of immunologic biomarkers, and a dietary intake consisting of higher energy and fiber and lower total fat. The results of the study are useful for guiding health care programs aimed at institutionalized elderly individuals.

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Section: Methodsmentioning

confidence: 99%

Frequency of metabolic syndrome and associated factors in institutionalized elderly individuals

Sales

Oliveira

Liberalino³

et al. 2018

CIA

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“…Age-adjusted time of institutionalization was calculated to determine how much time after the advanced age period (as a percentage, defined as the time after turning 60 years of age) elderly individuals remained institutionalized, according to a previous study [28].…”

Section: Methodsmentioning

confidence: 99%

“…Food consumption data were collected according to the method of weighed food records (WFRs), as described by Sales et al (2018) [28]. Habitual intake of each nutrient was estimated by removing the effect of intrapersonal variance, based on the method developed by Nusser et al (1996) [40].…”

Section: Methodsmentioning

confidence: 99%

High Prevalence of Hypovitaminosis D in Institutionalized Elderly Individuals is Associated with Summer in a Region with High Ultraviolet Radiation Levels

et al. 2019

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Vitamin D may play a significant role in regulating the rate of aging. The objective of the study was to assess vitamin D status and its associated factors in institutionalized elderly individuals. A total of 153 elderly individuals living in Nursing Homes (NH) were recruited into the study. Serum 25-hydroxyvitamin D [25(OH)D] concentration was used as the biomarker of vitamin D status, and it was considered as the dependent variable in the model. The independent variables were the type of NH, age-adjusted time of institutionalization, age, sex, skin color, body mass index, waist and calf circumference, physical activity practice, mobility, dietary intake of vitamin D and calcium, vitamin D supplementation, use of antiepileptics, and season of the year. Serum 25(OH)D concentrations less than or equal to 29 ng/mL were classified as insufficient vitamin D status. The prevalences of inadequate dietary intake of vitamin D and calcium were 95.4% and 79.7%, respectively. The prevalence of hypovitaminosis D was 71.2%, and the mean serum concentration of 25(OH)D was 23.9 ng/mL (95% confidence interval [CI]: 22.8–26.1). Serum 25(OH)D concentration was associated with the season of summer (p = 0.046). There were no associations with other independent variables (all p > 0.05). The present results showed that a high prevalence of hypovitaminosis D was significantly associated with summer in institutionalized elderly individuals.

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“…Zinc deficiency causes dysregulation of immune function, resulting in increased levels of inflammatory cytokines (i.e., interleukin-6 and tumour necrosis factor α), alongside deterioration of the antioxidant protection of cells and an increase in susceptibility to infection [59]. Dietary zinc deficiency is also associated with increased oxidative stress, playing a role in determining the pathologies of cardiovascular diseases in the elderly.…”

Section: Zincmentioning

confidence: 99%

Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review

et al. 2020

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The global population is ageing with many older adults suffering from age-related malnutrition, including micronutrient deficiencies. Adequate nutrient intake is vital to enable older adults to continue living independently and delay their institutionalisation, as well as to prevent deterioration of health status in those living in institutions. This systematic review investigated the insufficiency of trace minerals in older adults living independently and in institutions. We examined 28 studies following a cross-sectional or cohort design, including 7203 older adults (≥60) living independently in 13 Western countries and 2036 living in institutions in seven Western countries. The estimated average requirement (EAR) cut-off point method was used to calculate percentage insufficiency for eight trace minerals using extracted mean and standard deviation values. Zinc deficiency was observed in 31% of community-based women and 49% of men. This was higher for those in institutional care (50% and 66%, respectively). Selenium intakes were similarly compromised with deficiency in 49% women and 37% men in the community and 44% women and 27% men in institutions. We additionally found significant proportions of both populations showing insufficiency for iron, iodine and copper. This paper identifies consistent nutritional insufficiency for selenium, zinc, iodine and copper in older adults.

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Plasma zinc in institutionalized elderly individuals: Relation with immune and cardiometabolic biomarkers

Cited by 21 publications

References 34 publications

Frequency of metabolic syndrome and associated factors in institutionalized elderly individuals

Frequency of metabolic syndrome and associated factors in institutionalized elderly individuals

High Prevalence of Hypovitaminosis D in Institutionalized Elderly Individuals is Associated with Summer in a Region with High Ultraviolet Radiation Levels

Trace Mineral Intake and Deficiencies in Older Adults Living in the Community and Institutions: A Systematic Review

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