Plasma L. E. Test in Systemic Lupus Erythematosus

Hereditary Hypergammaglobulinaemia and Systemic Lupus Erythematosus

“…Nor were L. E. cells found in 1 of the patients with otherwise typical S. L. E. (A 111: 19), nor in the case with "essential" hypergammaglobulinaemia (A I11 : 22). Considering the fact that the L. E. cell phenomenon occurs preferentially in acute bouts of S. L. E. (Haserick 1951), the inability to demonstrate this phenomenon in the cases mentioned or in their relatives was not astonishing.…”

Disseminated Lupus Erythematosus : A Clinico‐pathological Review of Seven Cases

“…Haserick and Lewis (1950) have demonstrated that the formation of L.E. cells depends upon the presence of an abnormal factor in the y globulin fraction of the plasma, and Haserick (1951) suggests that the cell may be absent if the serum globulin level is low.…”