Plasma‐deposited AgOx‐doped TiOx coatings enable rapid antibacterial activity based on ROS generation

Abstract

To enable a rapid-acting antibacterial mechanism without the release of biocidal substances, TiO 2 catalysts have been considered based on the generation of reactive oxygen species (ROS). Doping with dissimilar metals generates electron-hole pairs with narrow band gaps promoting the production of ROS.Here, plasma technology is investigated to deposit Ag nano islets on defective TiOx films, stabilized by plasma postoxidation suppressing Ag ion release. Importantly, ROS generation is maintained upon storage in the dark yet with diminishing efficacy; however, it can be restored by exposure to visible light. The rapid-acting antibacterial properties are found to strongly correlate with ROS generation, which can even be maintained by functionalization with hydrophobic plasma polymer films. The cytocompatible coatings offer promising applications for implants and other medical devices.

Specific capture of Pseudomonas aeruginosa for rapid detection of antimicrobial resistance in urinary tract infections

“…One bacterial colony of every bacterial strain from an agar plate was taken and incubated in 10 mL LB in a 50 mL Falcon tube at 160 rpm and 37 • C overnight. 100 μL overnight culture was added into 10 mL fresh LB and subsequently cultivated for approximately 2 h to reach exponential growth (Guo et al, 2022;Hegemann et al, 2022;Milionis et al, 2020).…”

Hybrid-biotaxonomy-like machine learning enables an anticipated surface plasmon resonance of Au/Ag nanoparticles assembled on ZnO nanorods

“…Hybrid biotaxonomy aspect plays a crucial role in biotechnology, agriculture, clinical diagnosis, veterinary medicine, et al Taxonomy is applied in different systems, e.g., mammalian systems, insect expression systems, bacterial systems, filament fungi, yeasts, and unicellular cells 15,[46][47][48][49][50][51][52][53][54][55][56][57] . Escherichia coli is thereby extensively used thanks to the fast growth kinetics and low production costs 58,59 , consequently leading to a substantial application for protein taxonomy through various plasmid expression 59,60 .…”

Robust Antibacterial Activity of Xanthan-Gum-Stabilized and Patterned CeO2–x–TiO2 Antifog Films

“…Among various antibacterial materials, Ag nanoparticles embedded in films have prominent antimicrobial properties, but the oxidation of silver is detrimental to the antibacterial activity. ,,, However, modified surfaces, which can release antimicrobial agents or metal ions (Ag + , Cu 2+ , and Zn 2+ ) to inhibit bacterial colonization, can cause critical issues such as cytotoxicity, short antimicrobial durability, and resistance. − Contact-killing surfaces exploit either incorporated natural macromolecules, e.g., polysaccharides, or material surfaces (e.g., TiO 2 ), generating reactive oxygen species (ROS) to confer antibacterial activity. , ROS concentration and the resultant antibacterial efficacy on TiO 2 -based surfaces rely on the duration of UV irradiation and humid surrounding. − However, both Ag + ions and ROS manifest better antibacterial activity toward Escherichia coli than Staphylococcus aureus, likely caused by different bacterial membrane structures. ,,, …”