Plasma cholinesterase activity in hepatic diseases

Araoud, Manel; Mhenni, H; Hellara, Ilhem; Hellara, O.; Neffati, Fadoua; Mili, Marwa; Saffar, Hiva; Najjar, Mohamed Fadhel

doi:10.1684/abc.2013.0819

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…and CHE was reducedin fish fed the PEC and SBM diets compared with fish fed the CON diet, which supported liver tissue inflammatory changes (Araoud et al, 2013;Hu et al, 2017). Meanwhile, the expression of IL1β and NF-κβ1 was up-regulated (Figure 4).…”

Section: Discussionmentioning

confidence: 64%

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

Cai

Ren

et al. 2021

Aquaculture Research

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Dietary fibre (DF) is defined as 'non-digestible carbohydrates plus lignin' and includes non-starch polysaccharides (NSPs), hydrocolloids, resistant starch, resistant oligosaccharides and lignin associated with DF polysaccharides (Stephen et al., 2017). DF is not digested and absorbed by monogastric animals (Sinha et al., 2011), but can be fermented by intestinal microbiota (Miao et al., 2018).Therefore, it can regulate the structure of intestinal microbiota and improve intestinal health (Lin et al., 2020). In addition, DF has bile acid (BA) binding capacity Naumann et al., 2019) and reduces its reabsorption (Moriceau et al., 2000).BAs are synthesized from cholesterol. Therefore, appropriate DF intake can decrease cholesterol (Chen et al., 2018) and hepatic steatosis (Brockman et al., 2014). However, the effect of excessive DF intake on fish, which occurs with an increasing number of plant ingredients being included in the diet, has not received enough attention.

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Section: Discussionmentioning

confidence: 64%

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

Cai

Ren

et al. 2021

Aquaculture Research

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“…The levels of ALB and CHE were always decreased in cirrhotic patients [22]. The levels of ALB and CHE were always decreased in cirrhotic patients [22].…”

Section: Discussionmentioning

confidence: 90%

Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks

Yang

Zhou

et al. 2014

European Journal of Gastroenterology &Amp; Hepatology

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“…Changes in BChE activity are observed in various diseases and poor health condition [ 35 , 36 ]. Reduced plasma cholinesterase activity was reported in diseases associated with injury of the hepatic parenchyma [ 37 , 38 ] such as liver fibrosis, hepatitis and cirrhosis [ 39 ]. Individuals with confirmed liver cirrhosis present a 5-fold lower level of BChE than healthy controls [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

“…Individuals with confirmed liver cirrhosis present a 5-fold lower level of BChE than healthy controls [ 1 ]. It has been found that the fall of enzyme activity is more pronounced in liver cirrhosis patients than in hepatitis patients [ 38 ]. Moreover, cholinesterases have been considered as a useful marker of the effect of primary malnutrition on hepatic function [ 39 ].…”

Section: Discussionmentioning

confidence: 99%

Decreased activity of butyrylcholinesterase in blood plasma of patients with chronic obstructive pulmonary disease

Sicińska

Bukowska

Pająk

et al. 2017

aoms

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IntroductionButyrylcholinesterase (BChE) is involved in the metabolism of endogenous lipids and xenobiotics, such as esters of carboxylic or phosphoric acids. Butyrylcholinesterase activity is associated with both inflammation and oxidative stress. Changes in the activity of this enzyme have been observed in various diseases such as liver cirrhosis, diabetes, neurodegenerative disease and others.Material and methodsThe study involved 30 patients with chronic obstructive pulmonary disease (COPD) and 18 healthy subjects. The COPD patients were divided according to the severity of the disease by applying the classification of COPD based on GOLD standards for forced expiratory volume in 1 s (FEV1) and the FEV1/forced expiratory volume (FVC) ratio. The control group comprised blood samples collected from healthy subjects without concomitant diseases related to the respiratory system. Butyrylcholinesterase activity, lipid peroxidation and total antioxidant capacity (TAC) were determined in the blood plasma.ResultsA significant (p < 0.05) decrease in the activity of BChE, associated with an increase in lipid peroxidation and a decrease in the total antioxidant capacity, was observed in blood plasma of patients with chronic obstructive pulmonary disease.ConclusionsThe study shows for the first time that activity of BChE in the blood plasma of patients diagnosed with chronic obstructive pulmonary disease is considerably reduced compared with healthy subjects. These changes were accompanied by a decrease of TAC and an increase of lipid peroxidation, which suggests that they may be related to the oxidative stress induced by COPD disease.

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Plasma cholinesterase activity in hepatic diseases

Cited by 3 publications

References 7 publications

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

Pectin and soybean meal induce stronger inflammatory responses and dysregulation of bile acid (BA) homeostasis than cellulose and cottonseed meal, respectively, in largemouth bass ( Micropterus salmoides ), which might be attributed to their BA binding capacity

Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks

Decreased activity of butyrylcholinesterase in blood plasma of patients with chronic obstructive pulmonary disease

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