Plasma Ascorbic Acid Levels in Nigerian Mothers and Newborn

Ibeziako, P. A.; Ette, S. I.

doi:10.1093/tropej/27.5.263

Cited by 9 publications

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“…The ratio of ascorbic acid in newbom to mother was 1.6 in this study (Table 1 ). On the contrary limited permeability of lipid soluble antioxidants across the placenta lowers their concentration in cord blood (14,15,16). A positive correlation between mother and newborn levels of ascorbic acid and tocopherol indicates that the nutritional status of mother does influence antioxidant status of the newbom (17).…”

Section: Methodsmentioning

confidence: 99%

Antioxidant status and peroxidative stress in mother and newborn —A pilot study

Upadhyaya

Mishra

Singh

et al. 2005

Indian J Clin Biochem

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Serum antioxidant status and peroxidative stress was estimated in 30 pregnant women, their newborn infants and 25 non-pregnant women. Serum Ascorbic acid, cr retinol & ~-carotene levels were found to be significantly reduced and peroxidatlve stress was significantly higher in mothers as compared to matched non-pregnant women. Newborn had significantly higher levels of ascorbic acid as compared to their mother but had significantly lower levels of lipid soluble vitamins. The peroxidative stress in newbom was found to be significantly less as compared to their mothers. A positive correlation of ascorbic acid and ct-tocopherol levels between mother and newborn reflects that their status in mother does influence the newborn status.

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Section: Methodsmentioning

confidence: 99%

Antioxidant status and peroxidative stress in mother and newborn —A pilot study

Upadhyaya

Mishra

Singh

et al. 2005

Indian J Clin Biochem

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“…Vitamin C levels in the third trimester has been shown to be lower than the levels in the first and second trimester due to physiological changes in pregnancy leading to hemodilution[ 3 ] and deficiency of Vitamin C may be associated with some complications in pregnancy. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

Low serum Vitamin C status among pregnant women attending antenatal care at general hospital Dawakin Kudu, Northwest Nigeria

2016

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Background:Vitamin C levels are low in pregnancy. The purpose of this study was to determine serum Vitamins C levels among pregnant women attending antenatal care at a General Hospital in Dawakin Kudu, Kano, and this can help further research to determine the place of Vitamin C supplementation in pregnancy.Methods:This was a prospective study of 400 pregnant women who presented for antenatal care in General Hospital Dawakin Kudu, Kano, Nigeria. Research structured questionnaire was administered to 400 respondents. Determination of serum Vitamin C was done using appropriate biochemical methods.Results:Vitamin C deficiency was found in 79.5% of the participants. The values for Vitamin C were 0.20 ± 0.18 mg/dl during the first trimester, 0.50 ± 0.99 mg/dl in the second trimester, and 0.35 ± 0.36 mg/dl in the third trimester and P = 0.001.Conclusions:There is a significant reduction in the serum Vitamins C concentration throughout the period of pregnancy with the highest levels in the second trimester. Therefore, Vitamin C supplementation is suggested during pregnancy, especially for those whose fruit and vegetable consumption is inadequate.

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“…22,21 In contrast, limited permeability of lipid soluble antioxidants (like vitamin E) across the placenta lowers their concentration in cord blood. 23,24,15 However the mechanism of vitamin E transportation from mother to fetus has not been clarifi ed. 14 A positive correlation between mother and newborn levels of vitamin C and vitamin E shows that the nutritional status of mother infl uence antioxidant vitamin status of the newborn.…”

Section: Discussionmentioning

confidence: 99%

Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population

et al. 2016

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Background: New evidence suggests that excessive production of reactive oxygen species give rise to oxidative stress which could impair fetal growth. Antioxidant vitamin C and vitamin E have vital role in physiological process of pregnancy and health of the developing fetus.Aims and Objectives: To determine the concentrations of vitamin C and vitamin E in pair-matched maternal and cord serum of newborns and to determine the relationship between maternal/cord serum vitamin C and vitamin E at delivery and birth outcomes.Materials and Methods: A total of 209 maternal and cord blood samples were collected during delivery for serum vitamin C and E determination. Birth outcomes; birth weight, birth length, head circumference, and Apgar score were determined.Result: Newborns had significantly higher levels of vitamin C as compared to their mothers, but had non-significant lower level of vitamin E. Levels of vitamin C and E in both maternal and cord serum were positively correlated to birth weight, birth length, head circumference and Apgar score.Conclusion: Maternal vitamin C and E had significant effects on birth outcomes. A positive correlation of vitamin C and E indicates that their status in mother does influence newborns status.Asian Journal of Medical Sciences Vol.7(4) 2016 49-54

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Plasma Ascorbic Acid Levels in Nigerian Mothers and Newborn

Cited by 9 publications

References 0 publications

Antioxidant status and peroxidative stress in mother and newborn —A pilot study

Antioxidant status and peroxidative stress in mother and newborn —A pilot study

Low serum Vitamin C status among pregnant women attending antenatal care at general hospital Dawakin Kudu, Northwest Nigeria

Maternal to fetal transfer of vitamin C and vitamin E: effect on birth outcome in a Nigerian population

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