“…Our results are compatible with observations made from studies of tuberous sclerosis sera. The disorder is characterised by elevated serum alkaline phosphatase (Sareen, Ruvalcuba, Scotvold, Mahoney and Kelley, 1972;Fischer, Fortune and Gertisen, 1974;Rundle, Atkin and Dollimore, 1975) and increased aj-macroglobulin, a glycoprotein (Fischer et al, 1974;Rundle and Atkin, 1976) and several acute-phase reactant proteins (Rundle, 1976). These latter serum proteins which are also glycoproteinaceous are elevated in neoplastic conditions as well (Apffel and Peters, 1969).…”