Abstract:–
The present study contains data from a 4‐week clinical study where the effect of an experimental toothpaste containing 0.4% SnF2 on plaque and gingivitis was tested in a group of teenagers. The study was performed according to a double‐blind, cross‐over design. It was shown that the SnF2 containing toothpaste reduced both plaque and gingivitis significantly compared to a placebo paste which contained no fluoride or stannous ions.
“…Studies have also found a positive effect from the use of SnF2 on plaque in vitro (Andres et al, 1974) and on clinical plaque levels (Konig, 1959;Tinanoff et al, 1976;Svatun et al, 1977;Ogaard et al, 1980;White and Taylor, 1979;Bay and R0lla, 1980). In this study, the lower levels for the Plaque Index in the high-Sn2+ group ( Fig.…”
For nine months we monitored the periodontal health of 81 adolescents undergoing orthodontic treatment with fixed appliances, to determine whether daily use of a brush-on 0.4% SnF2 gel would be better than toothbrushing alone in maintaining periodontal health in these patients, and whether a gel supplying a high percentage of available Sn2+ ion would be more beneficial than a gel supplying a low percentage of available Sn2+ ion. The subjects were matched for age and sex and placed into a control group, which used toothbrushing alone, and two treatment groups, which used toothbrushing supplemented with daily use of a SnF2 gel. One treatment group used a gel with 98% available Sn2+ ion twice daily for the entire nine months. The other treatment group used a gel with less than 2% available Sn2+ once a day for six months, then twice a day for the remaining three months of the study. Clinical assessments (Plaque Index, Gingival Index, Bleeding Tendency, pocket depth, and coronal staining) were made before appliances were placed and at one, three, six, and nine months after appliances were placed. Results indicated that the group using the high-availability Sn2+ gel twice daily had significantly lower Gingival Index and Bleeding Tendency scores at the one-, three-, six-, and nine-month examinations than did the control group. The group using the low-availability Sn2+ gel showed no significant differences in these assessments from the control group. Neither treatment group showed significant differences from the control group in Plaque Index or pocket depth. In the group using the high-availability Sn2+ gel, one subject developed mild coronal staining, and two developed moderate staining.
“…Studies have also found a positive effect from the use of SnF2 on plaque in vitro (Andres et al, 1974) and on clinical plaque levels (Konig, 1959;Tinanoff et al, 1976;Svatun et al, 1977;Ogaard et al, 1980;White and Taylor, 1979;Bay and R0lla, 1980). In this study, the lower levels for the Plaque Index in the high-Sn2+ group ( Fig.…”
For nine months we monitored the periodontal health of 81 adolescents undergoing orthodontic treatment with fixed appliances, to determine whether daily use of a brush-on 0.4% SnF2 gel would be better than toothbrushing alone in maintaining periodontal health in these patients, and whether a gel supplying a high percentage of available Sn2+ ion would be more beneficial than a gel supplying a low percentage of available Sn2+ ion. The subjects were matched for age and sex and placed into a control group, which used toothbrushing alone, and two treatment groups, which used toothbrushing supplemented with daily use of a SnF2 gel. One treatment group used a gel with 98% available Sn2+ ion twice daily for the entire nine months. The other treatment group used a gel with less than 2% available Sn2+ once a day for six months, then twice a day for the remaining three months of the study. Clinical assessments (Plaque Index, Gingival Index, Bleeding Tendency, pocket depth, and coronal staining) were made before appliances were placed and at one, three, six, and nine months after appliances were placed. Results indicated that the group using the high-availability Sn2+ gel twice daily had significantly lower Gingival Index and Bleeding Tendency scores at the one-, three-, six-, and nine-month examinations than did the control group. The group using the low-availability Sn2+ gel showed no significant differences in these assessments from the control group. Neither treatment group showed significant differences from the control group in Plaque Index or pocket depth. In the group using the high-availability Sn2+ gel, one subject developed mild coronal staining, and two developed moderate staining.
“…Several studies have reported that frequent application of high concentration fiuorides may reduce gingivitis (Ringelberg 1979, Bay & Rolla 1980, Leverett et al 1984. Some suggest that amine fiuoride and stannous fiuoride may be particularly effective against plaque microorganisms (Muhlemann 1983, Tinanoff 1985, Newman et al 1985.…”
In recent years, tremendous strides have been made in understanding the etiology of gingivitis. This increase in knowledge has come, for the most part, from basic research in oral microbiology, immunology, histology and pathology. Over the past decade, less progress has been made in further refining the epidemiological relationships between gingivitis and various host and environmental factors. The major restraint has been the great difficulty in reliably measuring gingival inflammation. This problem has resulted in great inter- and intra-study variation in diagnosing the prevalence and severity of gingivitis in human populations. Consequently, it is almost impossible to estimate longitudinal trends in gingivitis and it is nearly as difficult to make comparisons among different population groups studied by different examiners. Nevertheless, by focusing on the most apparent and robust epidemiological relationships, an instructive overview of the epidemiology of gingivitis can be gained. A number of host and environmental factors have been studied in relation to gingivitis and some of these will be reviewed. With respect to age, there is general concensus that marginal gingivitis begins in early childhood, increases in prevalence and severity to the early teenage years, thereafter subsiding slightly and leveling off for the remainder of the second decade of life. Gingivitis during the adult period is much more difficult to characterize due to paucity of data. Estimates of the general prevalence of adult gingivitis vary from approximately 50 to 100% for dentate subjects. In terms of gingivitis prevalence, the dentate elderly do not deviate appreciably from the general adult pattern. When adjusted for cohort effects, gingival disease appears to be on the decline.(ABSTRACT TRUNCATED AT 400 WORDS)
“…been unsuccessful because of incompatibility Since daily mechanical removal of plaque by with some of the normal dentifrice ingredi-ents (8), A recent study (9) has confirmed that a 0.8% chlorhexidine (CHX) dentifrice, although it exhibited some ability to reduce plaque, was less effective than a 1% GHX gel. Other recent studies have shown that metal salts such as stannous fluoride and zinc citrate retain their antiplaque activity when incorporated into dentifrices (10)(11)(12)(13)(14).…”
– The effect upon plaque growth of adding a nonionic antimicrobial agent, triclosan, to a dentifrice containing zinc citrate was established in short‐term in vivo studies. Plaque regrowth was inhibited by brushing with dentifrices which contained either zinc citrate or triclosan. When both were combined in the same dentifrice, the inhibition of overnight plaque regrowth was significantly greater. In two 4‐day non‐brushing studies, the dentifrices containing both zinc citrate and triclosan were applied either undiluted by the use of a cap splint or as 23% suspensions in water. Both methods resulted in significant reductions in plaque accumulation, with the greater activity being observed for the undiluted application of the dentifrice. Analysis of results of the overnight plaque studies for individual teeth revealed that the two agents had a complementary inhibitory action on plaque regrowth, zinc citrate being more effective on existing plaque whereas triclosan inhibited plaque formation on clean surfaces. The dentifrice containing both agents was effective against both existing plaque and new plaque formation. It is concluded that the addition of triclosan to a dentifrice containing zinc citrate improves its antiplaque potential.
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