Plants and Plant Constituents with Analgesic and Anti-inflammatory Activities: A Systematic Review

Abstract

Medicinal plants with potential therapeutic activities are a tremendous resources of prospective drug candidates. NSAIDs, opiates, and other anti-inflammatory & analgesic agents exhibit several unwanted side-effects. Thus, the development of new active compounds with minimum adverse effects necessitates an emergence. This study aims to provide a comprehensive summary of plant species and reported phytoconstituents with analgesic and inti-inflammatory activities. Eighty-seven species from fifty-two plant families with reported constituents and activities have been included in this review. In-depth research in the area of screening novel analgesic and antiinflammatory agents from natural sources followed by the investigation of their pharmacological properties and clinical applications may lead to the generation of new active agents with better therapeutic activity and selectivity in the future.
 Dhaka Univ. J. Pharm. Sci. 19(2): 207-224, 2020 (December)

Phytochemical screening and antibacterial activity of Skimmia anquetilia N.P. Taylor and Airy Shaw: A first study from Kashmir Himalaya

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Multifaceted Chemico-Pharmacological Insights into Cynometra ramiflora L.: Unveiling its GC-MS, Cytotoxic, Thrombolytic, Anti-Inflammatory, Antioxidant, Anti-Diarrheal, Hypoglycemic, and Analgesic Potentials

“…69,70 Natural pain relievers are being looked into as alternatives to synthetic drugs because they have fewer side effects. 71 In this investigation, the findings suggest that the plant's methanolic extract elicited a slight reduction in pain perception at the central analgesic level (Table S3 and Figure 9). However, peripheral analgesic assessments unveiled a notable alleviation of acetic acid-induced pain sensation in mice (Table S4 and Figure 10).…”

Chemical and Pharmacological Profiling of Wrightia coccinea (Roxb. Ex Hornem.) Sims Focusing Antioxidant, Cytotoxic, Antidiarrheal, Hypoglycemic, and Analgesic Properties

“…Pain-relieving agents are being searched from natural sources as alternatives to synthetic drugs because they have fewer adverse effects [85]. In our study, the analgesic activity of methanol extract of the bark and methanol extracts of the fruit coat was evaluated by tail immersion method and writhing method in mice.…”