Plants: A Source for New Antimycobacterial Drugs

Abstract

alkaloids l " flavonoids l " chalcones l " coumarins l " lignans l " phenols l " terpenes l " chromones l " alkane l " alkene l " plants l " Mycobacterium tuberculosis

Anti-Tubercular Activities and Molecular Characterization of Salivary Extract of Leech (<i>Hirudo medicinalis</i>) against <i>Mycobacterium tuberculosis</i>

“…The biological activity of the LSE may, perhaps, be due to the presence of fatty acid components, especially the oleic and palmitic fatty acids. Santhosh and Suriyarayanan [17], revealed that fatty acids such as oleic acid and linoleic acid exhibited activity against MDR forms of M. tuberculosis. In another study, Juan et al, [18] reported the anti-tubercular activity of linoleic, oleic and palmitic acids found in essential oils from Citrus species.…”

Natural Remedies against Multi-Drug Resistant <i>Mycobacterium tuberculosis</i>

“…Moreover [39], the majority of new drugs introduced in the United States are derived primarily from the plants. As discussed, most of the chemical drugs cause adverse effects and are costlier, therefore, nowadays there is an increasing inclinations towards the use of an alternative source of medicine, especially based on medicinal plants [40]. A number of medicinal plants have been reported for anti-mycobacterial activity across the globe [41]- [46].…”

In vitro antituberculosis activity of diterpenoids from the Vietnamese medicinal plant Croton tonkinensis

“…Different plant extracts containing a variety of terpenoids, such as monoterpenes, sesquiterpenes, diterpenes and triterpenes, have been reported to possess moderate to significant biological activity against M. tuberculosis [8,9]. Croton tonkinensis, belonging to the Euphorbiaceae family, is an herbal shrub that grows in tropical areas and is abundant in Vietnam.…”