Plant telomere-binding proteins

Kuchař, Milan

doi:10.1007/s10535-005-0067-9

Cited by 9 publications

(4 citation statements)

References 63 publications

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“…Similar complexes are also likely to exist in plants and these are particularly attractive to study due to the telomerase‐competent status (i.e., reversible telomerase activity regulation) of plant somatic cells [2,3]. A number of putative plant telomeric proteins have been found by homology searches of DNA and protein sequence databases and tested for their affinity to telomeric DNA sequences in vitro (reviewed in [4]). There is however very little data relevant to their telomeric function.…”

Section: Introductionmentioning

confidence: 99%

Mapping of interaction domains of putative telomere‐binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana

et al. 2008

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We previously searched for interactions between plant telomere-binding proteins and found that AtTRB1, from the single-myb-histone (Smh) family, interacts with the Arabidopsis POT1-like-protein, AtPOT1b, involved in telomere capping. Here we identify domains responsible for that interaction. We also map domains in AtTRB1 responsible for interactions with other Smh-family-members. Our results show that the N-terminal OB-fold-domain of AtPOT1b mediates the interaction with AtTRB1. This domain is characteristic for POT1-proteins and is involved with binding the G-rich-strand of telomeric DNA. AtPOT1b also interacts with AtTRB2 and AtTRB3. The central histone-globular-domain of AtTRB1 is involved with binding to AtTRB2 and 3, as well as to AtPOT1b. AtTRB1-heterodimers with other Smh-family-members are more stable than AtTRB1-homodimers. Our results reveal interaction networks of plant telomeres.

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Section: Introductionmentioning

confidence: 99%

Mapping of interaction domains of putative telomere‐binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana

et al. 2008

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“…LOC_Os01g40670, a novel DE&DAS gene, encodes a member of the Single Myb Histone (SMH) family protein, a plant-specific group of proteins involved in telomere structure and metabolism [ 71 ]. In control conditions, this gene produces two transcript isoforms, in equal proportions, that differ by removal or retention of the fifth intron ( Figure 3 B).…”

Section: Resultsmentioning

confidence: 99%

“…In control conditions, this gene produces two transcript isoforms, in equal proportions, that differ by removal or retention of the fifth intron ( Figure 3 B). The AS alters the C-terminal end of the predicted proteins, near a domain involved in stabilising protein dimer formation, known as the coiled-coil domain [ 71 ], suggesting the AS might affect protein function. We observed a significant up-regulation of this gene upon 24 h of heat stress (DE), where the proportion of intron-5-containing transcripts increased to 96% of the total transcripts (DAS; Figure 3 B), which might impact telomere function.…”

Section: Resultsmentioning

confidence: 99%

Reading between the Lines: RNA-seq Data Mining Reveals the Alternative Message of the Rice Leaf Transcriptome in Response to Heat Stress

Vitoriano

Calixto

2021

Plants

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Rice (Oryza sativa L.) is a major food crop but heat stress affects its yield and grain quality. To identify mechanistic solutions to improve rice yield under rising temperatures, molecular responses of thermotolerance must be understood. Transcriptional and post-transcriptional controls are involved in a wide range of plant environmental responses. Alternative splicing (AS), in particular, is a widespread mechanism impacting the stress defence in plants but it has been completely overlooked in rice genome-wide heat stress studies. In this context, we carried out a robust data mining of publicly available RNA-seq datasets to investigate the extension of heat-induced AS in rice leaves. For this, datasets of interest were subjected to filtering and quality control, followed by accurate transcript-specific quantifications. Powerful differential gene expression (DE) and differential AS (DAS) identified 17,143 and 2162 heat response genes, respectively, many of which are novel. Detailed analysis of DAS genes coding for key regulators of gene expression suggests that AS helps shape transcriptome and proteome diversity in response to heat. The knowledge resulting from this study confirmed a widespread transcriptional and post-transcriptional response to heat stress in plants, and it provided novel candidates for rapidly advancing rice breeding in response to climate change.

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“…The TRFL family 1 protein is not the only factor that can specifically bind to double-stranded plant telomere DNA in vitro [101]. Telomere binding proteins are not only considered to be essential components of the telomere structure but are also important components of the telomere metabolism involved in telomere length regulation and telomere protection [102]. For instance, a double-stranded telomeric repeat binding factor in Nicotiana tabacum, NgTRF1, is involved in the maintenance of telomere length and stability [103].…”

Section: Telomere Metabolismmentioning

confidence: 99%

Characteristics and Functions of MYB (v-Myb avivan myoblastsis virus oncogene homolog)-Related Genes in Arabidopsis thaliana

Wu,

Cao,

Wen

et al. 2023

Genes

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The MYB (v-Myb avivan myoblastsis virus oncogene homolog) transcription factor family is one of the largest families of plant transcription factors which plays a vital role in many aspects of plant growth and development. MYB-related is a subclass of the MYB family. Fifty-nine Arabidopsis thaliana MYB-related (AtMYB-related) genes have been identified. In order to understand the functions of these genes, in this review, the promoters of AtMYB-related genes were analyzed by means of bioinformatics, and the progress of research into the functions of these genes has been described. The main functions of these AtMYB-related genes are light response and circadian rhythm regulation, root hair and trichome development, telomere DNA binding, and hormone response. From an analysis of cis-acting elements, it was found that the promoters of these genes contained light-responsive elements and plant hormone response elements. Most genes contained elements related to drought, low temperature, and defense and stress responses. These analyses suggest that AtMYB-related genes may be involved in A. thaliana growth and development, and environmental adaptation through plant hormone pathways. However, the functions of many genes do not occur independently but instead interact with each other through different pathways. In the future, the study of the role of the gene in different pathways will be conducive to a comprehensive understanding of the function of the gene. Therefore, gene cloning and protein functional analyses can be subsequently used to understand the regulatory mechanisms of AtMYB-related genes in the interaction of multiple signal pathways. This review provides theoretical guidance for the follow-up study of plant MYB-related genes.

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Plant telomere-binding proteins

Cited by 9 publications

References 63 publications

Mapping of interaction domains of putative telomere‐binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana

Mapping of interaction domains of putative telomere‐binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana

Reading between the Lines: RNA-seq Data Mining Reveals the Alternative Message of the Rice Leaf Transcriptome in Response to Heat Stress

Characteristics and Functions of MYB (v-Myb avivan myoblastsis virus oncogene homolog)-Related Genes in Arabidopsis thaliana

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