Plant Pharmacogenomics: From Drug Discovery to Personalized Ethnomedicine

Babar, Mustafeez Mujtaba; Zaidi, Najam us Sahar Sadaf; Gul, Alvina

doi:10.1007/978-81-322-2172-2_25

Cited by 2 publications

(3 citation statements)

References 194 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Genome-wide association studies (GWAS) and candidate gene approaches identify genetic markers associated with pharmacokinetic and pharmacodynamic traits, drug metabolism, and adverse drug reactions [39]. Pharmacogenomic data facilitate personalized medicine approaches by guiding the selection of appropriate medicinal plant formulations and dosage regimens tailored to individual genetic profiles [40].…”

Section: Omics Technologies In Medicinal Plant Researchmentioning

confidence: 99%

“…6. Systems Biology: Systems biology integrates omics data from genomics, transcriptomics, proteomics, and metabolomics to model and simulate the complex interactions within biological systems [40]. Network-based approaches, such as metabolic pathway analysis, gene regulatory networks, and protein interaction networks, elucidate the interconnectedness of molecular components and pathways underlying medicinal plant traits [41].…”

Section: Omics Technologies In Medicinal Plant Researchmentioning

confidence: 99%

See 1 more Smart Citation

Exploring Bioinformatics Opportunities for Identification and Study of Medicinal Plants: A Comprehensive Review

gupta,

Khatoon,

singh

et al. 2024

Preprint

View full text Add to dashboard Cite

Medicinal plants have been a cornerstone of traditional medicine systems for centuries, offering a vast array of bioactive compounds with therapeutic potential. However, the identification, characterization, and elucidation of the pharmacological properties of these plants have often been challenging due to their complex chemical composition and diverse biological activities. Bioinformatics, with its interdisciplinary approach combining biology, computer science, and information technology, presents a powerful toolkit for the systematic study of medicinal plants. This review provides an overview of bioinformatics methodologies and resources that can facilitate the identification, phytochemical analysis, pharmacological investigation, and conservation of medicinal plants. It highlights the integration of omics technologies, computational algorithms, database resources, and molecular modeling techniques in advancing our understanding of medicinal plants' therapeutic potential and their applications in drug discovery and development.

show abstract

Section: Omics Technologies In Medicinal Plant Researchmentioning

confidence: 99%

Section: Omics Technologies In Medicinal Plant Researchmentioning

confidence: 99%

Exploring Bioinformatics Opportunities for Identification and Study of Medicinal Plants: A Comprehensive Review

gupta,

Khatoon,

singh

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Integration of advanced biological and pharmacological sciences like bioinformatics and pharmacogenomics can help in deciphering the molecular mechanisms involved in the activity of these phytochemicals. 66 Efforts shall be made to develop the phytochemical based pharmaceutical industry in order to ensure the availability of safe and therapeutically effective medicinal options to a larger population base.…”

Section: Future Perspectives and Conclusionmentioning

confidence: 99%

Flora of Pakistan: An ethnopharmacological perspective

Shahid

Waseem

et al. 2020

JSTMU

View full text Add to dashboard Cite

Ethnopharmacology relies on the knowledge and use of traditional medicinal plants in various human diseases. These plants are a source of nutritional, medicinal and financial support to a greater part of Pakistani population, both in rural and urban setting. Either in the crude form or prepared pharmaceutical formulations, these plants are considered an essential part of the health-care and support system. Being regulated mainly as a part of the Complementary and Alternate Medicine, the plants and their products are used for the treatment of ailments of different organ systems. Their applications vary from being used as tonics, protectants and aids to being used as cytotoxic and antibacterial agents. Pakistan has a variety of biogeographical components which serves as a rich source of medicinal plants. With a deep-rooted history of Unani and Ayurvedic systems in Pakistan, the empirical knowledge about these plants has passed from one generation to the next. Some of these have also been recorded in the historical books of medicine and the components derived from them, now form an essential part of the modern-day pharmaceutical industry. This review provides the information of the flora of medicinal importance acquired from the various parts of Pakistan. The detailed information will help the researchers to develop an understanding about the biological activity and efficacy of phytochemical present in these plants.

show abstract

Plant Pharmacogenomics: From Drug Discovery to Personalized Ethnomedicine

Cited by 2 publications

References 194 publications

Exploring Bioinformatics Opportunities for Identification and Study of Medicinal Plants: A Comprehensive Review

Exploring Bioinformatics Opportunities for Identification and Study of Medicinal Plants: A Comprehensive Review

Flora of Pakistan: An ethnopharmacological perspective

Contact Info

Product

Resources

About