Plant cytochrome p450

Bolwell, G. Paul; Bozak, Kristin R.; Zimmerlin, Alfred

doi:10.1016/s0031-9422(00)89567-9

Cited by 246 publications

(126 citation statements)

References 154 publications

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“…Instead, we identified an up-regulation of fatty acid biosynthesis of the acyl-carrier protein under early time points under reduced ammonium availability, which confirms the up-regulation of ACP gene expression that was found under drastic nitrogen deprivation (39). There may be two lines of reasoning for the early increase in short-chain fatty acids: First, the pathway of omega-hydroxylation of caprate and laurate within the MetaCyc database suggests that the increase could be related to Cyp-450 hydroxylase activity for plant defense (84). This could be an evolutionary conserved defense mechanism against abiotic stress.…”

Section: Discussionsupporting

confidence: 64%

System Response of Metabolic Networks in Chlamydomonas reinhardtii to Total Available Ammonium

Lee

Park

Barupal

et al. 2012

Molecular & Cellular Proteomics

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Section: Discussionsupporting

confidence: 64%

System Response of Metabolic Networks in Chlamydomonas reinhardtii to Total Available Ammonium

Lee

Park

Barupal

et al. 2012

Molecular & Cellular Proteomics

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“…The presence of this activity in the 150,000g supernatant is likely due to the fragility of the leukoplasts during enzyme isolation (Gleizes et al, 1983). However, limonene-6-hydroxylase, like many other Cyt P-450 oxygenases (Bolwell et al, 1994), is probably found in the ER. Hence, for the operation of the monoterpene pathway, the limonene formed in the leukoplasts must be transferred into the ER.…”

Section: Other Modes Of Regulationmentioning

confidence: 98%

“…For example, in vitro activity is frequently insufficient to account for carvone accumulation, probably because of difficulties in quantitatively extracting and assaying this enzyme. Limonene-6-hydroxylase is a Cyt P-450-dependent oxygenase (Bolwell et al, 1994) which is found in the light membrane (microsomal) fraction of the cell (H.J. Bouwmeester, M.C.J.M.…”

Section: Enzyme Controlmentioning

confidence: 99%

Biosynthesis of the Monoterpenes Limonene and Carvone in the Fruit of Caraway1

Bouwmeester¹,

Gershenzon

Konings³

et al. 1998

Plant Physiology

147

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“…The existence of P450(s) in higher plants was first proven in the early 1970s [36]. Accumulating evidence indicates that there is a multiplicity of P450(s) in plants [19] and they are best known and most studied for their oxygenase activity [1,16,36]. P450(s) have the capacity to attack a vast range of structurally unrelated chemicals to transform them into more polar, soluble products, diminishing or suppressing their toxicity [10].…”

mentioning

confidence: 99%

Enhanced activity of several herbicide-degrading enzymes: a suggested mechanism responsible for multiple resistance in blackgrass (Alopecurus myosuroides Huds.)

Letouzé

Gasquez

2003

Agronomie

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To cite this version:Anne Letouzé, Jacques Gasquez. Enhanced activity of several herbicide-degrading enzymes: a suggested mechanism responsible for multiple resistance in blackgrass (Alopecurus myosuroides Huds. Abstract -Experiments were carried out to analyse enhanced herbicide metabolism mediated by cytochrome P450 monooxygenases (P450(s)) or glutathione-S transferases (GST(s)) as a possible mechanism responsible for multiple resistance in three blackgrass populations. The RA population is resistant to aryloxyphenoxypropionates (fops) and flupyrsulfuron, the RB to fenoxaprop-P, flupyrsulfuron and ureas and the RC to fenoxaprop-P, haloxyfop and clodinafop. Based on the coleoptile length, growth responses of seedlings to the herbicide responsible for resistance and to combined treatments of the herbicide plus P450(s) or GST(s), inhibitors were compared. Growth of the RA seedlings was significantly reduced with flupyrsulfuron plus malathion, suggesting that P450(s) activity may be involved in the resistance. In contrast, none of the four inhitors tested had an effect on the fop resistance. Fenoxaprop-P plus tridiphane, flupyrsulfuron plus malathion and ureas plus PBO or ABT significantly reduced the RB coleoptiles' growth. Therefore, multiple resistance in this population may be due to an elevation of P450(s) and GST(s) activity. In the RC population, PBO, ABT and tridiphane synergised clodinafop, haloxyfop and fenoxaprop-P effects, suggesting that the two enzymatic systems may also be involved in the RC resistances. multiple herbicide resistance / enhanced herbicide detoxification / P450(s)/GST(s) / Alopecurus myosuroides Huds.Résumé -L'amplification d'enzymes de détoxication des herbicides : un mécanisme possible responsable des résistances multiples chez le vulpin (Alopecurus myosuroides Huds.). Cette expérimentation a pour but d'analyser l'éventuelle implication de monooxygénases à cytochrome P450 (P450(s)) et de glutathione S-transférases (GST(s)) dans les résistances multiples observées chez trois populations de vulpin. La population RA résiste aux aryloxyphenoxypropionates (fops) et au flupyrsulfuron, la RB au fénoxaprop-P, au flupyrsulfuron et aux urées et la RC au fénoxaprop-P, à l'haloxyfop et au clodinafop. Les croissances de la première feuille des plantules exposées à l'herbicide seul et à un mélange "herbicide + inhibiteur" ont été analysées. La croissance des plantules RA est fortement réduite en présence de flupyrsulfuron associé au malathion. Ainsi, des P450(s) pourraient être impliquées dans la résistance de cette population. En revanche, les quatre inhibiteurs sont sans effet sur la résistance aux fops. Comparées à l'effet des herbicides utilisés seuls, les combinaisons fénoxaprop-P plus tridiphane, flupyrsulfuron plus malathion et urées plus PBO ou ABT réduisent significativement la croissance des plantules RB. Ces résultats suggèrent donc que des P450(s) et des GST(s) pourraient être responsables des résistances multiples de cette population. Pour finir, les résistances de la population RC p...

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Plant cytochrome p450

Cited by 246 publications

References 154 publications

System Response of Metabolic Networks in Chlamydomonas reinhardtii to Total Available Ammonium

System Response of Metabolic Networks in Chlamydomonas reinhardtii to Total Available Ammonium

Biosynthesis of the Monoterpenes Limonene and Carvone in the Fruit of Caraway1

Enhanced activity of several herbicide-degrading enzymes: a suggested mechanism responsible for multiple resistance in blackgrass (Alopecurus myosuroides Huds.)

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