Planning Study for Funnel Breast Patients: Comparison between Tomotherapy and Electron IMRT using an Add-on Electron MLC

Gauer, Tobias; Engel, Konrad; Sokoll, J.; Grohmann, Carsten; Cremers, F.

doi:10.1016/j.ijrobp.2008.06.028

Cited by 3 publications

(2 citation statements)

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“…Our proposed optimization approaches were tested for different cancer indications, in particular for breast cancer patients with a funnel chest. For comparison with conventional irradiation and the more advanced IMRT version from TomoTherapy, we refer the reader to our previous studies (Gauer et al 2008a).…”

Section: Resultsmentioning

confidence: 99%

A dose optimization method for electron radiotherapy using randomized aperture beams

Engel¹,

Gauer²

2009

Phys. Med. Biol.

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The present paper describes the entire optimization process of creating a radiotherapy treatment plan for advanced electron irradiation. Special emphasis is devoted to the selection of beam incidence angles and beam energies as well as to the choice of appropriate subfields generated by a refined version of intensity segmentation and a novel random aperture approach. The algorithms have been implemented in a stand-alone programme using dose calculations from a commercial treatment planning system. For this study, the treatment planning system Pinnacle from Philips has been used and connected to the optimization programme using an ASCII interface. Dose calculations in Pinnacle were performed by Monte Carlo simulations for a remote-controlled electron multileaf collimator (MLC) from Euromechanics. As a result, treatment plans for breast cancer patients could be significantly improved when using randomly generated aperture beams. The combination of beams generated through segmentation and randomization achieved the best results in terms of target coverage and sparing of critical organs. The treatment plans could be further improved by use of a field reduction treatment plans could be further improved by use of a field reduction algorithm. Without a relevant loss in dose distribution, the total number of MLC fields and monitor units could be reduced by up to 20%. In conclusion, using randomized aperture beams is a promising new approach in radiotherapy and exhibits potential for further improvements in dose optimization through a combination of randomized electron and photon aperture beams.

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Section: Resultsmentioning

confidence: 99%

A dose optimization method for electron radiotherapy using randomized aperture beams

Engel¹,

Gauer²

2009

Phys. Med. Biol.

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“…Estes feixes são empregados em uma série de modernos tratamentos radioterápicos, como tratamentos com intensidade modulada feixe (IMRT) (Gauer, 2008), radiocirurgia, radioterapia com arco de elétrons, irradiação total da pele com elétrons (comumente chamada de TBI, do inglês: "Total Body Irradiation") e a radioterapia intra-operatória. (Metcalfe et al,2007) AL clínicos são máquinas que utilizam campos de freqüência da ordem das microondas e eiferença de potencial elétrico da ordem de milhões de elétrons volts para acelerar elétrons em uma linha reta.…”

Section: Aceleradores Lineares Clínicosunclassified

Avaliação dosimétrica da solução fricke gel usando a técnica de espectrofotometria para aplicação na dosimetria de elétrons e nêutrons

Mangueira¹

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Comparison of electron IMRT to helical photon IMRT and conventional photon irradiation for treatment of breast and chest wall tumours

Gauer

Engel

Kiesel

et al. 2010

Radiotherapy and Oncology

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Planning Study for Funnel Breast Patients: Comparison between Tomotherapy and Electron IMRT using an Add-on Electron MLC

Cited by 3 publications

References 0 publications

A dose optimization method for electron radiotherapy using randomized aperture beams

A dose optimization method for electron radiotherapy using randomized aperture beams

Avaliação dosimétrica da solução fricke gel usando a técnica de espectrofotometria para aplicação na dosimetria de elétrons e nêutrons

Comparison of electron IMRT to helical photon IMRT and conventional photon irradiation for treatment of breast and chest wall tumours

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