Placental insufficiency and fetal growth restriction: etiology, prevention, and treatment

Тапильская, Н. И.; Мельников, К. Н.; Kuznetsova, Irina A.; Glushakov, Ruslan I.

doi:10.33667/2078-5631-2020-4-6-10

Cited by 4 publications

(1 citation statement)

References 28 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Основные причины КР в старшем возрасте -различные нейродегенеративные, цереброваскулярные заболевания и дисметаболические нарушения. Факторы риска развития болезни Альцгеймера (БА) можно разделить на модифицируемые и немодифицируемые: существенный фактор риска развития -пожилой и старческий возраст (риск развития БА в течение 1 года для различных возрастных групп составляет: 65-69 лет -0,3%, 70-74 года -0,6%, 75-80 лет -0,9%, 80-84 года -2,3%, 85-89 лет -4%, старше 90 лет -6,9%) [10][11]. Среди других немодифицируемых факторов риска семейный анамнез БА, особенно при раннем начале заболевания (до 65 лет), и носительство генетических полиморфизмов, наличие аллеля АПОЕ4, женский пол, черепно-мозговые травмы в анамнезе [1].…”

Section: связь женского пола и нейродегенеративных заболеванийunclassified

Menopausal hormone therapy and Alzheimer’s disease: A literature review

Luzik,

Isaeva,

Svidinskaya

et al. 2024

V.F.Snegirev Archives of Obstetrics and Gynecology

View full text Add to dashboard Cite

This paper presents a review of the current literature on the possible relationship between menopausal hormone therapy and Alzheimer’s disease. Increasing life expectancy in modern society is steadily leading to health problems in older women. Approximately 46.8 million people worldwide currently have cognitive disorders, and 2/3 of them are women. At the age of ≥65 years, every sixth woman and every eleventh man experience a form of higher nervous system pathologies. Older people are most often diagnosed with Alzheimer’s disease. It is a neurodegenerative disease that leads to problems with memory and cognitive functions and is characterized by changes in behavior and social-adaptive position of a person in society. One theory states that dementia is caused by changes in the endocrine status during menopause, particularly a decrease in estrogen levels. Currently, hormonal drugs are being considered a way to reduce the risk of neurological disorders. The possibility of preventing dementia, particularly Alzheimer’s disease, has long been of interest to leading experts in this field. The prevention of these diseases and prolongation of active longevity are becoming more relevant than ever. The relationship between menopausal hormone therapy and the risk of Alzheimer’s disease is receiving increasing attention.

show abstract

Section: связь женского пола и нейродегенеративных заболеванийunclassified

Menopausal hormone therapy and Alzheimer’s disease: A literature review

Luzik,

Isaeva,

Svidinskaya

et al. 2024

V.F.Snegirev Archives of Obstetrics and Gynecology

View full text Add to dashboard Cite

show abstract

Features of the course of pregnancy and health of newborns with intrauterine growth restriction

Volochaeva,

Kan,

Tyutyunnik

et al. 2023

Medicinskij sovet

View full text Add to dashboard Cite

Introduction. The development of intrauterine growth restriction (IUGR) begins with fertilization and trophoblast invasion. IUGR is manifested in a decrease in fetal growth rate. However, data on risk factors for fetal growth retardation, their combination with various chronic diseases in a pregnant woman are contradictory.Objective. To study the features of the course of pregnancy, childbirth, the health status of newborns with IUGR. Materials and methods. The study was a retrospective cohort study. At the first stage, we analyzed 1574 birth histories with a diagnosis of IUGR, placental insufficiency, women with normal pregnancy who gave birth (2016–2021). According to the inclusion and exclusion criteria, 408 women were included in the study. The women were divided into 2 groups. The first group included 202 pregnant women with a diagnosis of IUGR. In the second Group – 206 pregnant women with normal pregnancy, without IUGR, delivered at the time corresponding to the terms in the main group.Results. We have clarified the risk factors and premorbid conditions involved in the development of IUGR (somatic and gynecological morbidity, pregnancy course). Their analysis is necessary to predict IUGR. The analysis of the timing and method of delivery in the studied groups was carried out. A higher incidence of complications in the early neonatal period was revealed when assessing the health status of newborns with IUGR.Conclusion. Thus, the study of the mechanisms of IUGR formation in the future will allow the development of modern pathogenetic approaches to prevention and treatment.

show abstract

Daily periodicity of labor in pregnant women in physiological and complicated pregnancy depending on the sex of the fetus

Боташева

Andreeva

Lebedenko

et al. 2021

Med. vestn. Ûga Ross.

View full text Add to dashboard Cite

Objective: the study aimed to reveal the daily periodicity of labor, the nature of melatonin metabolism, and the outcome of childbirth in women with a physiological and complicated pregnancy, depending on the sex of the fetus.Materials and methods: to study the chronophysiological characteristics of birth outcomes depending on fetal sex, 1 980 birth histories and stories of newborns were analyzed. The neonates were born between January 1 and December 31, 2016, in a maternity ward of the Federal State Budgetary Educational Institution of Higher Education “RostGMU” of the Ministry of Health of Russia. Melatonin production was identified by the level of urinary excretion of 6-sulfatoxymelatonin (6-SM) (its main metabolite) examining the morning portion of the urine of women by the ELISA method (at 8 am 3 ml of urine were collected in Eppendorf tube).Results: it was revealed that fetal sex modulated the activity of the central regulatory mechanisms responsible for the daily period functional processes in the female body and the initiation of labor. The largest number of spontaneous births by male fetuses occurred in the early evening before midnight when daily illumination was decreased, while the birth of girls was observed more often in the period from midnight to early morning. At the same time, mothers of boys had lower production of melatonin compared to that of girls’ mothers.Conclusions. The peculiarities of labor and birth complications associated with the sex of the fetus were identified.

show abstract

Placental insufficiency and fetal growth restriction: etiology, prevention, and treatment

Cited by 4 publications

References 28 publications

Menopausal hormone therapy and Alzheimer’s disease: A literature review

Menopausal hormone therapy and Alzheimer’s disease: A literature review

Features of the course of pregnancy and health of newborns with intrauterine growth restriction

Daily periodicity of labor in pregnant women in physiological and complicated pregnancy depending on the sex of the fetus

Contact Info

Product

Resources

About