Place du zolpidem dans le traitement des catatonies résistantes aux benzodiazépines. À propos d’un cas

Hlal, Hayat; Kettani, N. Ech-Chrif El; Berhili, Nabil; Rammouz, Ismaïl; Aalouane, Rachid

doi:10.1016/j.lpm.2013.11.023

Cited by 6 publications

(7 citation statements)

References 10 publications

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“…In a subsequent publication of the same French group, the authors confirm a prompt response (i.e., reduction of at least 50% of symptoms) in all patients 20 min after the administration of 10 mg zolpidem, at a plasma level of 80–150 ng/L ( 29 ). These favorable results are replicated in a few case reports ( 100 – 102 ). In some instances, the beneficial response to zolpidem occurred after treatment with benzodiazepines and/or ECT had failed ( 98 , 101 , 102 ).…”

Section: Treatment Of Catatoniamentioning

confidence: 60%

“…These favorable results are replicated in a few case reports ( 100 – 102 ). In some instances, the beneficial response to zolpidem occurred after treatment with benzodiazepines and/or ECT had failed ( 98 , 101 , 102 ). These data have led to the proposition of a Zolpidem Challenge Test (see higher), and have urged some clinicians to continue treatment with zolpidem instead of benzodiazepines, using doses from 7.5 to 40 mg per day, without noticeable adverse effects.…”

Section: Treatment Of Catatoniamentioning

confidence: 60%

“…These data have led to the proposition of a Zolpidem Challenge Test (see higher), and have urged some clinicians to continue treatment with zolpidem instead of benzodiazepines, using doses from 7.5 to 40 mg per day, without noticeable adverse effects. Even though the short-half life results in a transient effect on symptoms, long-term treatment with zolpidem has also been described ( 101 , 102 ).…”

Section: Treatment Of Catatoniamentioning

confidence: 99%

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A Clinical Review of the Treatment of Catatonia

Sienaert¹,

Dhossche²,

Vancampfort³

et al. 2014

Front. Psychiatry

235

312

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Catatonia is a severe motor syndrome with an estimated prevalence among psychiatric inpatients of about 10%. At times, it is life-threatening especially in its malignant form when complicated by fever and autonomic disturbances. Catatonia can accompany many different psychiatric illnesses and somatic diseases. In order to recognize the catatonic syndrome, apart from thorough and repeated observation, a clinical examination is needed. A screening instrument, such as the Bush-Francis Catatonia Rating Scale, can guide the clinician through the neuropsychiatric examination. Although severe and life-threatening, catatonia has a good prognosis. Research on the treatment of catatonia is scarce, but there is overwhelming clinical evidence of the efficacy of benzodiazepines, such as lorazepam, and electroconvulsive therapy.

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Section: Treatment Of Catatoniamentioning

confidence: 60%

Section: Treatment Of Catatoniamentioning

confidence: 60%

Section: Treatment Of Catatoniamentioning

confidence: 99%

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A Clinical Review of the Treatment of Catatonia

Sienaert¹,

Dhossche²,

Vancampfort³

et al. 2014

Front. Psychiatry

235

312

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“…В качестве альтернативы бензодиазепинам рассматривается возможность применения небензодиазепиновых модуляторов ГАМК-рецепторов. В ряде публикаций сообщается о результативном использовании золпидема в качестве фармакологического инструмента верификации наличия кататонии (золпидемовый тест) [52] и ее терапии [53,54]. S. Peglow и соавт.…”

Section: бензодиазепиныunclassified

Therapy of Catatonia in Schizophrenia and Schizophrenia Spectrum Disorders

Ivanov

Borisova

et al. 2022

Psychiatry

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Background: the study of catatonia’s treatment methods is one of the most important researchers’ tasks, nevertheless the common therapeutic strategies of cupping the catatonic phenomena haven’t been created yet. The aim: review to therapeutic interventions for catatonic disorders in schizophrenia.Materials and methods: according to the keywords “catatonia treatment”, “catatonia therapy”, publications found in the Scopus, PubMed, Cochrane Library, eLibrary databases were selected and analyzed.Results: historical background, illustrating the development of catatonia treatment methods, is given; the results of the last decades scientific studies of catatonia’s treatment and preliminary results of own study, devoted to the effectiveness of diazepam and cariprazine in relieving catatonia manifestations are presented. Based on the studies’ results, presented in the review, it can be concluded that the most common modern method of treating catatonic disorders is the use of benzodiazepines, however, in some cases, the use of antipsychotics is also advisable. Electroconvulsive therapy (ECT) remains an important treatment for catatonic phenomena. There are also isolated clinical cases of successful testing of both: other pharmacological groups (antidepressants, dopaminergic and anticholinergic drugs, normothymic drugs, etc.) and non-drug interventions (transcranial magnetic stimulation — TMS) presented in modern research data.Conclusion: the effectiveness of benzodiazepines in catatonia, associated with schizophrenia and schizophrenia spectrum disorders (SSD), remains controversial according to modern authors’ opinion. In turn, among antipsychotics, antipsychotics of the second and third generation seem to be safe for the treatment of psychomotor symptoms. In accordance with the results of our own study, catatonia in the structure of schizophrenia and SSD is heterogeneous and, depending on the psychopathological structure of catatonic disorders, a different reaction of psychomotor symptoms to therapeutic intervention was observed.

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“…Positive symptoms include: bizarre postures of body segments maintained for extended intervals of time, catalepsy (lack of response to stimuli, slowing of movements until the occurrence of bizarre positions), mannerisms, stereotypes, catatonic agitation with aggressive behavior that may occur in complete catatonic state, suggestibility manifested by motor automatisms expressed as automatic acts of response to the surrounding demands, ecopraxia, ecolalia and ecomimia (known as the ecopathic triad) (1, 3,4). The negative symptoms are presented by: catatonic stupor, negativism (resistance to the request to execute certain demands, to answer the interlocutor's questions), mute (the complete absence of any verbal emission), ambitendence (contrary tendencies that appear to be in conflict) (4,5…”

mentioning

confidence: 99%

Catatonic syndrome – positive and differential diagnostic controversies. Case study

Aniculăesei¹,

Radu²,

Boloș³

et al. 2019

BPI

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The present paper is the presentation of a case that exposes a positive and differential diagnosis controversy, in the context of a catatonic syndrome with a sudden onset, occurring in an apparent state of mental health, in a patient of 42 years old, without personal or heredocolateral psychiatric history, with normal premorbid functioning. Its purpose is to emphasize the importance of excluding organicity in the case of catatonic syndrome and to make it aware that the impact of the often impressive psychotic symptoms should not overshadow the detection of potentially life-threatening somatic symptoms. The presented case underlines precisely the dilemma of establishing the etiology of catatonic syndrome, between endogenous causes and underdiagnosed meningeal reaction.

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Place du zolpidem dans le traitement des catatonies résistantes aux benzodiazépines. À propos d’un cas

Cited by 6 publications

References 10 publications

A Clinical Review of the Treatment of Catatonia

A Clinical Review of the Treatment of Catatonia

Therapy of Catatonia in Schizophrenia and Schizophrenia Spectrum Disorders

Catatonic syndrome – positive and differential diagnostic controversies. Case study

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